Travoprost
**Travoprost** is a topical ophthalmic prostaglandin F2α analogue used primarily in veterinary medicine for the management of **primary canine glaucoma**. It is highly effective at rapidly reducing intraocular pressure (IOP) and is often utilized in the emergency management of acute primary glaucoma. It has comparable activity to latanoprost and is frequently used in conjunction with other topical antiglaucoma drugs, such as carbonic anhydrase inhibitors. > **Clinical Warning:** Travoprost is contraindicated in cases of uveitis and anterior lens luxation, though it may be useful in managing lens subluxation and posterior luxation. Avoid use in pregnant animals.
Mecanismo: Acts as an agonist for **prostaglandin F receptors** → increases **uveoscleral outflow** of aqueous humor → significantly reduces **intraocular pressure (IOP)**.
Dosificación por especie
- Primary glaucoma / Lens subluxation / Posterior luxation · 1 drop per eye · topical · once daily (evening), or q8-12h · Often used in conjunction with other topical antiglaucoma drugs such as carbonic anhydrase inhibitors.
Las dosis son una referencia clínica para médicos veterinarios. Confirme siempre con la información vigente del producto y el paciente individual.
Vías de administración
Contraindicaciones
- Uveitis
- Anterior lens luxation
- Pregnancy
Efectos adversos
- Miosis (profound in dogs)
- Conjunctival hyperaemia
- Mild ocular irritation
- Increased iridal pigmentation (noted in humans, but not typically in dogs)
Interacciones farmacológicas
- Thiomersal-containing preparations · Incompatible; do not use in conjunction · major
Monitoreo
- Intraocular pressure (IOP)
- Signs of ocular irritation or inflammation
- Pupil size (miosis)
Sobredosis
No specific veterinary information provided. Overdosage is likely to cause profound miosis, conjunctival hyperaemia, and ocular irritation. Flush the eye with sterile saline if significant accidental overexposure occurs.
La referencia de fármacos de VetSheet está destinada a médicos veterinarios como apoyo a la decisión clínica; no sustituye el juicio profesional ni la información vigente del fabricante.