Sodium hypochlorite / Hypochlorous acid
**Sodium hypochlorite** (in the form of pH-balanced **hypochlorous acid**) is a topical antimicrobial and wound care agent. It assists in the mechanical removal of cellular debris, senescent cells, necrotic tissue, and foreign material from the skin and wound surface through debridement. It possesses broad-spectrum **antibacterial and antifungal action**. > **Clinical Pearl:** Unlike traditional bleach or Dakin's solution, modern veterinary hypochlorous acid formulations are pH-balanced to a physiological range, making them non-cytotoxic to healing fibroblasts and safe for use on delicate tissues.
Mecanismo: Hypochlorous acid (HOCl) is a potent oxidizing agent naturally produced by neutrophils during the oxidative burst. * **Mechanical action:** The spray application assists in the physical debridement and flushing of cellular debris and necrotic tissue. * **Antimicrobial action:** HOCl → oxidizes sulfhydryl enzymes and amino acids → disrupts bacterial cell walls and biofilms → leads to microbial cell death.
Dosificación por especie
- Wounds and skin infections · Spray affected areas · topical · bid · Until healed · Spray up to twice daily
- Wounds and skin infections · Spray affected areas · topical · bid · Until healed · Spray up to twice daily
Las dosis son una referencia clínica para veterinarios colegiados. Confirme siempre con la ficha técnica vigente y el paciente individual.
Vías de administración
Contraindicaciones
- None reported
Efectos adversos
- None reported
Monitorización
- Wound healing progress
- Reduction in signs of local infection (erythema, purulent discharge)
- Signs of secondary or worsening infection requiring systemic therapy
Sobredosis
Overdosage is highly unlikely due to the topical route of administration and the non-toxic, physiological nature of the pH-balanced formulations. Ingestion of small amounts from grooming is generally considered safe.
La referencia de fármacos de VetSheet está destinada a veterinarios colegiados como apoyo a la decisión clínica, no sustituye el juicio profesional ni la ficha técnica vigente del fabricante.