ドキュセートナトリウム / ドキュセートカルシウム

動物種別の用量

用量は獣医療従事者向けの臨床リファレンスです。必ず最新の添付文書と個々の患者で確認してください。

投与経路

禁忌

• Pre-existing fluid or electrolyte abnormalities (use with caution)

有害事象

• Cramping
• Diarrhea
• Intestinal mucosal damage (especially at high doses)
• Throat irritation (liquid preparations)
• Bitter taste (can cause hypersalivation/foaming in cats)

薬物相互作用

• Mineral Oil · Theoretically enhances absorption of mineral oil. Not a significant concern in large animals, but concurrent use in dogs/cats is not recommended. If both are necessary in small animals, separate doses by at least 2 hours. · major

モニタリング

• Clinical efficacy (resolution of constipation/impaction)
• Hydration status
• Electrolyte status (if indicated or in high doses)

過量投与

In **horses**, single doses of 0.65-1 g/kg have caused dehydration, intestinal mucosal damage, and death. Maximum therapeutic dosages of up to 0.2 g/kg have been reported. * **Clinical Signs (Horses)**: Begin 1-2 hours after dosing. Initial signs include restlessness and increased intestinal sounds, followed by increased respiratory and cardiac rates. Abdominal pain, watery diarrhea, and dehydration can occur, deteriorating over hours to days to lateral recumbency and death. * **Treatment**: Supportive care. Because of the secretory effects of high doses, hydration and electrolyte status must be monitored and corrected. GI protectants, bicarbonate, corticosteroids, and antiendotoxemic agents (NSAIDs) have been suggested as potentially helpful.