아트라쿠륨

동물 종별 용량

용량은 면허 수의 전문가를 위한 임상 참고 자료입니다. 항상 최신 라벨과 개별 환자에 대해 확인하십시오.

투여 경로

금기

• Conscious or inadequately anesthetized animals
• Lack of positive pressure ventilation facilities
• Lack of trained personnel to monitor neuromuscular blockade
• Conscious animals (must NEVER be administered unless the animal is adequately anesthetized)

이상반응

• Histamine release (especially with rapid IV injection)
• Bronchospasm
• Hypotension
• Tachycardia
• Histamine release (especially with rapid IV administration)

약물 상호작용

• Volatile anaesthetics · Prolonged neuromuscular blockade · major
• Aminoglycosides · Prolonged neuromuscular blockade · moderate
• Clindamycin · Prolonged neuromuscular blockade · moderate
• Lincomycin · Prolonged neuromuscular blockade · moderate

모니터링

• Neuromuscular function (using a peripheral nerve stimulator / Train-of-Four)
• Respiratory rate and effort (mechanical ventilation parameters)
• End-tidal CO2 (capnography)
• Oxygen saturation (pulse oximetry)
• Heart rate and rhythm (ECG)
• Blood pressure
• Core body temperature
• Neuromuscular function (using a peripheral nerve stimulator/Train-of-Four monitor)
• Respiratory rate, effort, and end-tidal CO2
• Heart rate and blood pressure
• Core body temperature (hypothermia prolongs effect)
• Acid-base status and potassium levels

과용량

Overdosage results in **prolonged neuromuscular blockade** and respiratory paralysis. * **Management:** Requires continuous mechanical positive pressure ventilation until spontaneous recovery occurs. * **Reversal:** Pharmacological reversal agents (e.g., neostigmine or edrophonium) combined with an anticholinergic (e.g., atropine or glycopyrrolate to prevent severe bradycardia) should be administered once signs of spontaneous recovery begin (confirmed via nerve stimulator).