부피바카인

동물 종별 용량

용량은 면허 수의 전문가를 위한 임상 참고 자료입니다. 항상 최신 라벨과 개별 환자에 대해 확인하십시오.

투여 경로

금기

• Intravenous (IV) administration
• Intravenous regional anaesthesia (Bier block)
• Use of adrenaline-containing formulations at end-arterial sites (e.g., tail, digits, ears)
• Use of adrenaline-containing formulations when significant systemic absorption is likely

이상반응

• Severe cardiac arrhythmias (if injected intravascularly)
• Motor blockade (paresis/paralysis of affected limbs)
• CNS toxicity (seizures, tremors) at high systemic doses
• Hypotension (especially with epidural use)

약물 상호작용

• Other local anaesthetics (e.g., lidocaine, mepivacaine) · Additive systemic toxicity; doses must be reduced when used concurrently. · major

모니터링

• Aspiration for blood prior to injection (mandatory)
• Electrocardiogram (ECG) during and after block placement
• Blood pressure
• Respiratory rate and effort (especially with epidural or intrapleural use)
• Motor function recovery

과용량

Overdose or inadvertent IV injection leads to profound **CNS toxicity** (muscle twitching, seizures, coma) and **cardiovascular toxicity** (profound hypotension, bradycardia, ventricular arrhythmias, asystole). > **Clinical Pearl:** Bupivacaine-induced cardiac arrest is notoriously resistant to standard CPR. **Intravenous Lipid Emulsion (ILE) therapy** (e.g., Intralipid 20%) is the specific antidote and should be administered immediately alongside standard resuscitation efforts.