카스포펀진

동물 종별 용량

용량은 면허 수의 전문가를 위한 임상 참고 자료입니다. 항상 최신 라벨과 개별 환자에 대해 확인하십시오.

투여 경로

금기

• Hypersensitivity to caspofungin
• Significant hepatic impairment

이상반응

• Histamine-mediated signs (rash, facial swelling, pruritus)
• Anaphylaxis
• Intravenous site reactions (pain, redness, phlebitis)
• Hepatic dysfunction

약물 상호작용

• Carbamazepine · Reduced caspofungin plasma levels
• Cyclosporine · Increased caspofungin plasma levels and increased risk of hepatic enzyme increases
• Dexamethasone · Reduced caspofungin plasma levels
• Phenytoin · Reduced caspofungin plasma levels
• Rifampin · Reduced caspofungin plasma levels

모니터링

• Clinical efficacy
• Periodic liver function tests
• CBC
• Serum electrolytes

과용량

Limited information is available for veterinary patients. - **Humans**: Dosages of 210 mg (about 3X normal) were well tolerated. - **Primates**: Monkeys receiving 5-8 mg/kg (approx. 4-6X normal) over 5 weeks developed sites of microscopic subcapsular necrosis on their livers.