세파클러

동물 종별 용량

용량은 면허 수의 전문가를 위한 임상 참고 자료입니다. 항상 최신 라벨과 개별 환자에 대해 확인하십시오.

투여 경로

금기

• Known hypersensitivity to cephalosporins
• Use with caution in patients with documented penicillin allergy (potential cross-reactivity)
• Severe renal impairment (requires dosage adjustment)

이상반응

• Nausea
• Diarrhea
• Hypersensitivity reactions (including anaphylaxis)
• Serum-sickness-like reactions
• Erythema multiforme (rare)
• Rash
• Transient increases in liver enzymes
• Transient increases in BUN and serum creatinine

약물 상호작용

• Antacids (magnesium or aluminum-containing) · Reduces extent of absorption of extended-release cefaclor tablets
• Probenecid · Reduced renal excretion of cefaclor
• Warfarin · Rare reports of increased anticoagulant effect

모니터링

• Clinical efficacy (resolution of infection)
• Renal function in patients with pre-existing renal insufficiency

과용량

Cefaclor appears quite safe in dogs. * **Chronic high doses:** Dogs given daily PO doses of 200 mg/kg/day for 30 days developed soft stools, occasional emesis, and transient moderate decreases in hemoglobin. * **Massive chronic doses:** One dog given 400 mg/kg/day for one year developed a reversible thrombocytopenia.