세프포독심 프록세틸

동물 종별 용량

용량은 면허 수의 전문가를 위한 임상 참고 자료입니다. 항상 최신 라벨과 개별 환자에 대해 확인하십시오.

투여 경로

금기

• Hypersensitivity to cefpodoxime or other cephalosporins

이상반응

• Inappetence
• Diarrhea
• Vomiting
• Hypersensitivity reactions
• Positive direct Coombs' test
• Blood dyscrasias (rare, following high doses)

약물 상호작용

• Aminoglycosides / Nephrotoxic drugs (e.g., amphotericin B) · Potentially additive nephrotoxicity (controversial). In vitro synergy exists, but do not mix together in the same syringe/fluid.
• Antacids · Drugs that increase stomach pH may decrease the absorption of cefpodoxime.
• H-2 Antagonists (ranitidine, famotidine) · Drugs that increase stomach pH may decrease the absorption of cefpodoxime.
• Probenecid · Competitively blocks tubular secretion of cephalosporins, increasing serum levels and half-lives.
• Proton Pump Inhibitors (omeprazole) · Drugs that increase stomach pH may decrease the absorption of cefpodoxime.

모니터링

• Clinical efficacy (resolution of infection)
• Adverse GI effects

과용량

Cephalosporin overdoses are unlikely to cause significant problems. The most likely signs of acute toxicity or overdose are gastrointestinal disturbances (vomiting, diarrhea, inappetence). Supportive care should be provided if necessary.