๋๋ ธํ ํธ๋
๋๋ ธํ ํธ๋์ 3์ธ๋ ๋ค์ค๋์ฝํฐ๋ ธ์ด๋๊ณ ์ด์ถฉ์ ๋ก, ์์ํ์์๋ ์ฃผ๋ก ๊ตญ์์ฉ ๋ฒผ๋ฃฉ ์ฑ์ถฉ ๊ตฌ์ ์ ๋ก ์ฌ์ฉ๋ฉ๋๋ค. **์์ ํ:** ๊ฐ์์๋ ๊ด๋ฒ์ํ ์ธ๋ถ๊ธฐ์์ถฉ ๊ตฌ์ ๋ฅผ ์ํด ํผ๋ฉํธ๋ฆฐ(์ง๋๊ธฐ/๋ชจ๊ธฐ ๊ธฐํผ ๋ฐ ๊ตฌ์ ์ ) ๋ฐ ํผ๋ฆฌํ๋ก์ํ(๊ณค์ถฉ ์์ฅ ์กฐ์ ์ )๊ณผ ํผํฉํ์ฌ ์ฌ์ฉํ๋ ๊ฒฝ์ฐ๊ฐ ๋ง์ต๋๋ค. > **๊ฒฝ๊ณ :** ํผ๋ฉํธ๋ฆฐ์ด ํฌํจ๋ ์ ํ(์: Vectra 3D)์ ๊ณ ์์ด์๊ฒ ๋งค์ฐ ์น๋ช ์ ์ธ ๋ ์ฑ์ ๋ํ๋ ๋๋ค.
์์ฉ ๊ธฐ์ : Dinotefuran acts as an agonist at insect **nicotinic acetylcholine receptors (nAChRs)**. It binds continuously to these receptors โ causes continuous nerve stimulation โ leads to tremors, paralysis, and death of the insect. **Synergistic activity** is observed when combined with permethrin in vitro and in vivo.
๋๋ฌผ ์ข ๋ณ ์ฉ๋
- Flea, tick, and flying insect control ยท 6.4 mg dinotefuran/kg, 0.6 mg pyriproxyfen/kg and 46.6 mg permethrin/kg ยท topical ยท q4w ยท Continuous during parasite season ยท Apply topically to the skin as a spot-on. Vectra 3D formulation.
์ฉ๋์ ๋ฉดํ ์์ ์ ๋ฌธ๊ฐ๋ฅผ ์ํ ์์ ์ฐธ๊ณ ์๋ฃ์ ๋๋ค. ํญ์ ์ต์ ๋ผ๋ฒจ๊ณผ ๊ฐ๋ณ ํ์์ ๋ํด ํ์ธํ์ญ์์ค.
ํฌ์ฌ ๊ฒฝ๋ก
๊ธ๊ธฐ
- Cats (specifically for permethrin-containing combination products like Vectra 3D)
- Known hypersensitivity to neonicotinoids
์ด์๋ฐ์
- Application site reactions (erythema, pruritus, alopecia)
- Lethargy
- Gastrointestinal upset if ingested (hypersalivation, vomiting)
๋ชจ๋ํฐ๋ง
- Efficacy of parasite control
- Application site for irritation or erythema
๊ณผ์ฉ๋
Overdose of topical dinotefuran alone is generally well tolerated in dogs. However, ingestion or massive overdose of combination products containing permethrin can lead to **pyrethroid toxicity** (tremors, seizures, hypersalivation, hyperthermia). Treatment is supportive (e.g., methocarbamol for tremors, bathing with dish soap to remove unabsorbed product).
VetSheet ์ฝ๋ฌผ ๋ ํผ๋ฐ์ค๋ ๋ฉดํ ์์ ์ ๋ฌธ๊ฐ๋ฅผ ์ํ ์์ ์์ฌ๊ฒฐ์ ๋ณด์กฐ ๋๊ตฌ์ด๋ฉฐ, ์ ๋ฌธ์ ํ๋จ์ด๋ ์ ์กฐ์ฌ์ ์ต์ ๋ผ๋ฒจ์ ๋์ ํ์ง ์์ต๋๋ค.