도큐세이트 나트륨 / 도큐세이트 칼슘

동물 종별 용량

투여 경로

금기

• Pre-existing fluid or electrolyte abnormalities (use with caution)

이상반응

• Cramping
• Diarrhea
• Intestinal mucosal damage (especially at high doses)
• Throat irritation (liquid preparations)
• Bitter taste (can cause hypersalivation/foaming in cats)

약물 상호작용

• Mineral Oil · Theoretically enhances absorption of mineral oil. Not a significant concern in large animals, but concurrent use in dogs/cats is not recommended. If both are necessary in small animals, separate doses by at least 2 hours. · major

모니터링

• Clinical efficacy (resolution of constipation/impaction)
• Hydration status
• Electrolyte status (if indicated or in high doses)

과용량

In **horses**, single doses of 0.65-1 g/kg have caused dehydration, intestinal mucosal damage, and death. Maximum therapeutic dosages of up to 0.2 g/kg have been reported. * **Clinical Signs (Horses)**: Begin 1-2 hours after dosing. Initial signs include restlessness and increased intestinal sounds, followed by increased respiratory and cardiac rates. Abdominal pain, watery diarrhea, and dehydration can occur, deteriorating over hours to days to lateral recumbency and death. * **Treatment**: Supportive care. Because of the secretory effects of high doses, hydration and electrolyte status must be monitored and corrected. GI protectants, bicarbonate, corticosteroids, and antiendotoxemic agents (NSAIDs) have been suggested as potentially helpful.