에스트리올

동물 종별 용량

용량은 면허 수의 전문가를 위한 임상 참고 자료입니다. 항상 최신 라벨과 개별 환자에 대해 확인하십시오.

투여 경로

금기

• Intact bitches
• Polyuria/polydipsia (PU/PD) of unknown origin
• Animals < 1 year old

이상반응

• Oestrogenic effects (swollen vulva, attractiveness to males) in 5-9% of dogs at 2 mg/day
• Bone marrow suppression (rare, but possible with long-term use)
• Gastrointestinal upset (mild)

약물 상호작용

• Phenylpropanolamine · Concurrent administration may potentiate efficacy in treating urinary incontinence (synergistic effect). · minor

모니터링

• Clinical response (resolution of urinary incontinence)
• Complete Blood Count (CBC) periodically for long-term use to monitor for bone marrow suppression
• Signs of estrogenic side effects (vulvar swelling)

과용량

Overdose may lead to exaggerated estrogenic effects, including pronounced vulvar swelling, attractiveness to male dogs, and potentially an increased risk of **bone marrow suppression** (anemia, thrombocytopenia, leukopenia). Treatment is supportive and symptomatic; discontinue the drug until signs resolve.