κ°λνν νΈμ°
κ°λνν νΈμ°μ μ기곡λͺ μμ(MRI) μ‘°μμ λ‘ μ¬μ©λλ μ ν μ΄μ¨μ± μμμ± κ°λ리λ ν¬λ μ΄νΈμ λλ€. λΉμ μμ μΈ νκ΄ νμ± λΆμλ₯Ό μλ³νκ³ , μ’ κ΄΄μ μ€κ³½μ 그리며, νμ‘λμ₯λ²½μ νκ΄΄ λ° μΌμ¦ λΆμλ₯Ό μ μ¦νλ λ° μ¬μ©λ©λλ€.
μμ© κΈ°μ : Gadolinium is a paramagnetic agent that exerts its effects due to **seven unpaired electrons** β causes a shortening of **T1 and T2 relaxation times** of adjacent tissues β results in increased signal intensity on T1-weighted MR images.
λλ¬Ό μ’ λ³ μ©λ
- MRI examination (CNS, whole body) Β· 0.1 mmol/kg Β· IV Β· single dose Β· Repeat doses up to 0.3 mmol/kg total may be helpful in some cases Β· Give as bolus if performing MRA, dynamic contrast or liver studies. Enhancement visible up to 45-60 minutes post-administration.
μ©λμ λ©΄ν μμ μ λ¬Έκ°λ₯Ό μν μμ μ°Έκ³ μλ£μ λλ€. νμ μ΅μ λΌλ²¨κ³Ό κ°λ³ νμμ λν΄ νμΈνμμμ€.
ν¬μ¬ κ²½λ‘
κΈκΈ°
- Severe renal impairment
μ΄μλ°μ
- Nephrogenic systemic fibrosis (reported in humans)
- Prolonged QT interval
- Arrhythmias
- Tissue irritation and necrosis if extravasated
- Anaphylaxis (rare, 0.001%-0.01% in humans)
- Transient increase in serum bilirubin
μ½λ¬Ό μνΈμμ©
- Class 1a antiarrhythmics Β· Potential interaction affecting cardiac rhythm Β· moderate
- Class 3 antiarrhythmics Β· Potential interaction affecting cardiac rhythm Β· moderate
λͺ¨λν°λ§
- Cardiac rhythm (in case of overdose)
- Renal function
κ³Όμ©λ
Accidental overdosage may lead to an increase in QT interval and other arrhythmias. **Cardiac monitoring** is recommended in the event of an overdose.
VetSheet μ½λ¬Ό λ νΌλ°μ€λ λ©΄ν μμ μ λ¬Έκ°λ₯Ό μν μμ μμ¬κ²°μ 보쑰 λꡬμ΄λ©°, μ λ¬Έμ νλ¨μ΄λ μ μ‘°μ¬μ μ΅μ λΌλ²¨μ λμ νμ§ μμ΅λλ€.