κ°μν΄λ‘λΉλ₯΄
κ°μν΄λ‘λΉλ₯΄λ μ£Όλ‘ **κ³ μμ΄ ν€λ₯΄νμ€λ°μ΄λ¬μ€-1(FHV-1)** μκ³Ό κ°μΌ κ΄λ¦¬μ μ¬μ©λλ νλ°μ΄λ¬μ€μ μ λλ€. μνκ΄ λ΄ μ°κ΅¬μ λ°λ₯΄λ©΄ FHV-1μ λν΄ μμν΄λ‘λ²λ³΄λ€ μ΅μ 10λ°° μ΄μ ν¨κ³Όμ μ λλ€. > **μμ κ²½κ³ :** μ 볡 λ°μ΄λ¬μ€ κ°μΌμ κ·Όμ ν μλ μμ΅λλ€. κ΅μ μ¬μ©μ λν μΌνμ μΈ λ³΄κ³ λ κΈμ μ μ΄λ, κ³ μμ΄μ λν μμ μ±μ΄λ μ½λνμ μμ ν λ³΄κ³ λμ§ μμμ΅λλ€. λμΉμ± λ° μ€μ¦ FHV-1 κΆ€μμ κ²½μ° κ΅μ λλ μ μ νλ°μ΄λ¬μ€μ λ₯Ό ν¬ν¨ν λ³μ© μλ²μ μ¬μ©ν μ μμ΅λλ€.
μμ© κΈ°μ : Ganciclovir inhibits **viral replication** by targeting **viral DNA polymerase**. It depends on **viral thymidine kinase** for initial phosphorylation β converted to active ganciclovir triphosphate by cellular enzymes β competitive inhibition of viral DNA polymerase β termination of viral DNA chain elongation.
λλ¬Ό μ’ λ³ μ©λ
- Ocular feline herpesvirus-1 (FHV-1) infections Β· Apply small amount to affected eye Β· topical Β· q4-6h Β· maximum 3 weeks Β· In refractory and severe cases, combined therapy can be used.
μ©λμ λ©΄ν μμ μ λ¬Έκ°λ₯Ό μν μμ μ°Έκ³ μλ£μ λλ€. νμ μ΅μ λΌλ²¨κ³Ό κ°λ³ νμμ λν΄ νμΈνμμμ€.
ν¬μ¬ κ²½λ‘
μ΄μλ°μ
- Ocular irritation
λͺ¨λν°λ§
- Resolution of clinical ocular signs (e.g., healing of corneal ulcers)
- Signs of ocular irritation or discomfort
κ³Όμ©λ
No specific information available. Overdose via topical ophthalmic route is unlikely to cause systemic toxicity, but may increase the risk of severe ocular irritation.
VetSheet μ½λ¬Ό λ νΌλ°μ€λ λ©΄ν μμ μ λ¬Έκ°λ₯Ό μν μμ μμ¬κ²°μ 보쑰 λꡬμ΄λ©°, μ λ¬Έμ νλ¨μ΄λ μ μ‘°μ¬μ μ΅μ λΌλ²¨μ λμ νμ§ μμ΅λλ€.