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3% 과산화수소

Hydrogen Peroxide 3%

Hydrogen peroxide

경구 최토제 / 국소 소독제POtopical고양이페렛돼지

다른 이름: Hydrogen Peroxide 3% Solution · Dilute hydrogen peroxide solution · Hydrogen peroxide solution 10-volume · Hydrogen peroxide topical solution

VetSheet 수의사 팀 검수업데이트 2026년 4월 5일근거 기반 수의학 참고자료

1 teaspoon (5 mL) per 5 lbs. (2.3 kg) of body weight (approximately 2 mL/kg) not to exceed 3 tablespoons (45 mL).PO· can be repeated once if not initially successful
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용량은 수의사 전문가를 위한 임상 참고자료입니다. 반드시 최신 약물 정보 및 개별 환자에 따라 확인하시기 바랍니다.

동물 종별 용량

🌎 NA — North America🌍 EU — Europe

적응증용량경로빈도기간지역
As an emetic1 teaspoon (5 mL) per 5 lbs. (2.3 kg) of body weight (approximately 2 mL/kg) not to exceed 3 tablespoons (45 mL).POcan be repeated once if not initially successful🌎 NA
As an emetic1-2 mL/kg PO up to 2-3 timesPOup to 2-3 times🌎 NA
As an emetic1-5 mL/kg PO; generally not to exceed 50 mL for dogs and 10 mL for cats; may repeat one time if after 10 minutes emesis does not occur.POmay repeat one time if after 10 minutes emesis does not occur🌎 NA
  • As an emetic: Vomiting usually occurs within minutes.
  • As an emetic: Inducing emesis is most effective if administered after a small meal.

고양이

적응증용량경로빈도기간지역
As an emetic1 teaspoon (5 mL) per 5 lbs. (2.3 kg) of body weight (approximately 2 mL/kg) not to exceed 3 tablespoons (45 mL).POcan be repeated once if not initially successful🌎 NA
As an emetic1-2 mL/kg PO up to 2-3 timesPOup to 2-3 times🌎 NA
As an emetic1-5 mL/kg PO; generally not to exceed 50 mL for dogs and 10 mL for cats; may repeat one time if after 10 minutes emesis does not occur.POmay repeat one time if after 10 minutes emesis does not occur🌎 NA
  • As an emetic: Vomiting usually occurs within minutes. Note: Use in cats is generally discouraged due to risk of severe gastric ulceration.
  • As an emetic: Inducing emesis is most effective if administered after a small meal.

페렛

적응증용량경로빈도기간지역
As an emetic1 teaspoon (5 mL) per 5 lbs. (2.3 kg) of body weight (approximately 2 mL/kg) not to exceed 3 tablespoons (45 mL).POcan be repeated once if not initially successful🌎 NA
As an emetic1-2 mL/kg PO up to 2-3 timesPOup to 2-3 times🌎 NA
As an emetic1-5 mL/kg PO; may repeat one time if after 10 minutes emesis does not occur.POmay repeat one time if after 10 minutes emesis does not occur🌎 NA
  • As an emetic: Vomiting usually occurs within minutes.
  • As an emetic: Inducing emesis is most effective if administered after a small meal.

돼지

적응증용량경로빈도기간지역
As an emetic (pot-bellied pigs)1 teaspoon (5 mL) per 5 lbs. (2.3 kg) of body weight (approximately 2 mL/kg) not to exceed 3 tablespoons (45 mL).POcan be repeated once if not initially successful🌎 NA
As an emetic (pot-bellied pigs)1-2 mL/kg PO up to 2-3 timesPOup to 2-3 times🌎 NA
As an emetic (pot-bellied pigs)1-5 mL/kg PO; may repeat one time if after 10 minutes emesis does not occur.POmay repeat one time if after 10 minutes emesis does not occur🌎 NA
  • As an emetic (pot-bellied pigs): Vomiting usually occurs within minutes.
  • As an emetic (pot-bellied pigs): Inducing emesis is most effective if administered after a small meal.

용량은 수의사 전문가를 위한 임상 참고자료입니다. 반드시 최신 약물 정보 및 개별 환자에 따라 확인하시기 바랍니다.

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개요

3% 과산화수소는 널리 사용되는 국소 소독제이며, 수의학에서는 주로 개에서 ​응급 경구 최토제​로 자주 사용됩니다.

  • ​임상 요점:​ 가정 상비약이지만, 최토제로서의 사용은 일반적으로 즉각적인 수의학적 치료가 불가능하고 신속한 오염 제거가 필요한 상황으로 제한됩니다. 임상 환경에서는 효능이 더 높고 심각한 점막 자극 위험이 낮은 ​아포모르핀​(개) 또는 ​크실라진/덱스메데토미딘​(고양이)과 같은 중추성 최토제가 선호됩니다.
  • ​고양이 주의사항:​ 심각한 괴사성 출혈성 위염을 유발할 위험이 높기 때문에 독성학자들은 고양이에게 사용하는 것을 점점 더 권장하지 않습니다.
  • ​효능:​ 구토 유발에 성공했다고 해서 위 내용물이 완전히 비워졌다는 것을 보장하지는 않습니다. 섭취한 약물/독소의 상당량이 남아 있거나 이미 흡수되었을 수 있습니다.

작용 기전

Orally administered hydrogen peroxide (3%) induces a vomiting reflex via direct irritant effects on the oropharynx and gastric lining.

  • ​Mechanism:​ H₂O₂ interacts with the enzyme catalase present in tissue and blood → rapid release of water (H₂O) and oxygen gas (O₂) → massive bubbling and gastric distension.
  • The combination of direct mucosal irritation and sudden gastric distension stimulates visceral afferent vagal and sympathetic nerves → signals the emetic center in the medulla oblongata → triggers the vomiting reflex.
  • Emesis typically ensues within 10 minutes of administration.

안전성·주의사항

금기사항

  • Animals already vomiting
  • Severely lethargic, comatose, or debilitated animals (e.g., respiratory distress, decreased swallowing reflex, bradycardia)
  • Seizuring or hyperactive animals
  • Recent abdominal surgery
  • Megaesophagus
  • Ingestion of corrosives/caustics (e.g., acids, alkalis)
  • Ingestion of sharp objects
  • Ingestion of bagged illicit drugs
  • Ingestion of hydrocarbons or petroleum distillates
  • Rodents or rabbits (incapable of vomiting)

부작용

  • Aspiration of hydrogen peroxide solution or stomach contents
  • Vasovagal (bradycardic) response in animals with cardiovascular compromise
  • Gastric ulceration (particularly in cats)
  • Gastric-dilatation-volvulus (GDV) in dogs

주의

​WARNING:​ Do not induce emesis in animals that lack a normal swallowing reflex or are severely depressed due to high aspiration risk.

  • ​Neurological Status:​ Use caution when attempting to induce emesis in a dog that has ingested a compound that can cause seizures or CNS depression, as CNS status may rapidly deteriorate.
  • ​Timeframe:​ Administration and emesis generally must occur within 4 hours (some say 2 hours or 6 hours maximum) of the toxic ingestion.
  • ​Product Safety:​ If home administration is necessary, ensure clients use ONLY the 3% medical grade solution. Higher concentrations are highly corrosive.
  • ​Monitoring:​ Because aspiration and/or bradycardia are possible, animals should be closely observed. Suctioning, respiratory, and cardiovascular support (e.g., atropine) should be available in a clinical setting.
  • ​Re-ingestion:​ Do not allow the animal to re-ingest vomitus.

약물 상호작용

ACETYLCYSTEINE (oral)

Hydrogen peroxide can oxidize acetylcysteine in the gut; alternative emetics are preferred for acetaminophen overdoses.

ANTIEMETICS (e.g., ondansetron, maropitant)

Preadministration or ingestion of these products may negate the emetic effects of hydrogen peroxide.

모니터링

  • Efficacy (emesis, signs associated with toxicity of the substance ingested, blood levels of toxicants if applicable)
  • Heart rate and respiration rate
  • Thoracic auscultation after emesis (to monitor for aspiration pneumonia)

과다투여

Hydrogen peroxide 3% solution is relatively non-toxic after oral ingestion, though it can cause gastric irritation, vomiting, and rarely gastric ulceration or GDV.

​DANGER:​ Hydrogen peroxide in concentrations of 10% or greater (such as hair bleach or industrial peroxide) can be very corrosive, causing severe burns to the oral and gastric mucosa, and can induce fatal oxygen emboli after oral ingestion.

제품

제형

  • 3% solution (2.5-3.5% w/v)

동물용의약품

  • None as an oral emetic

인용의약품

  • Hydrogen Peroxide 3% Solution (OTC, usually sold in pint bottles)

규제 현황

규제 데이터 없음: 🇺🇸 US · 🇪🇺 EU · 🇬🇧 UK · 🇭🇰 HK · 🇹🇼 TW · 🇯🇵 JP · 🇰🇷 KR · 🇦🇺 AU

보관·안정성

Store 3% solutions in airtight containers at room temperature and protected from light. Hydrogen peroxide 3% can deteriorate with time; outdated or improperly stored products may not be effective as an emetic.

보호자 정보

​응급 상황에만 사용:​ 수의사나 반려동물 독극물 관리 센터와 먼저 상담하지 않고 구토를 유발하지 마십시오. 일부 독소(배터리, 표백제 또는 날카로운 물건 등)는 다시 토해낼 때 심각한 손상을 일으킵니다!

  • ​올바른 제품 사용:​ 반드시 표준 ​3% 과산화수소​를 사용하십시오. 더 높은 농도(예: 염색약 산화제)는 매우 위험하고 부식성이 있습니다.
  • ​투여 방법:​ 투약용 주사기나 스포이드를 사용하여 입 옆으로 액체를 짜 넣으십시오. 반려동물이 액체를 폐로 흡입하지 않도록 목구멍으로 강제로 밀어 넣지 마십시오.
  • ​유용한 팁:​ 과산화수소를 투여하기 직전에 소량의 촉촉한 음식(빵 한 조각이나 약간의 통조림 사료 등)을 먹이면 위가 밀어낼 내용물이 생겨 구토 가능성을 높일 수 있습니다. 투여 후 개를 걷게 하는 것도 위에서 과산화수소가 잘 섞이도록 돕습니다.
  • ​사후 관리:​ 반려동물을 주의 깊게 지켜보십시오. 토사물을 다시 먹지 못하게 하십시오. 수의사가 검사할 수 있도록 토사물 샘플을 비닐봉지나 용기에 수집하십시오.

VetSheet 의약품 참고자료는 수의사 전문가의 임상 의사결정 지원을 위한 것이며, 전문적 판단이나 제조사의 최신 약물 정보를 대체할 수 없습니다.