이미다프릴

동물 종별 용량

용량은 면허 수의 전문가를 위한 임상 참고 자료입니다. 항상 최신 라벨과 개별 환자에 대해 확인하십시오.

투여 경로

금기

• Acute renal failure
• Congenital heart disease
• Hemodynamically relevant stenoses (e.g., aortic stenosis)
• Obstructive hypertrophic cardiomyopathy
• Hypovolemia
• Breeding, pregnant, or lactating bitches
• Dogs weighing < 4 kg (safety not established)

이상반응

• Hypotension
• Hyperkalemia
• Azotemia
• Anorexia (rare)
• Vomiting (rare)
• Diarrhea (rare)

약물 상호작용

• Spironolactone · Could result in hyperkalemia, though in practice, spironolactone and ACE inhibitors appear safe to use concurrently. · moderate
• Potassium supplements · Increased risk of hyperkalemia. · moderate
• NSAIDs · Increased risk of nephrotoxicity and decreased clinical efficacy of the ACE inhibitor. · major
• Diuretics · Increased risk of hypotension. · moderate
• Vasodilators (e.g., anesthetic agents, antihypertensives) · Increased risk of hypotension. · moderate
• Beta-blockers · Increased risk of hypotension when combined with negative inotropes. · moderate

모니터링

• Blood pressure
• Serum creatinine and BUN
• Serum electrolytes (especially potassium and sodium)
• Clinical signs of hypotension (weakness, syncope)

과용량

Doses of up to **5 mg/kg/day** have been well tolerated in healthy dogs. If overdosage occurs, monitor closely for signs of **hypotension** (weakness, lethargy, disorientation). If hypotension occurs, supportive care including intravenous fluids may be required.