이소프로테레놀

동물 종별 용량

용량은 면허 수의 전문가를 위한 임상 참고 자료입니다. 항상 최신 라벨과 개별 환자에 대해 확인하십시오.

투여 경로

금기

• Tachycardias or AV block caused by cardiac glycoside (digoxin) intoxication
• Ventricular arrhythmias that do not require increased inotropic activity

이상반응

• Tachycardia
• Ventricular arrhythmias (highly arrhythmogenic)
• Anxiety and excitability
• Tremors
• Headache
• Weakness
• Vomiting

약물 상호작용

• General Anesthetics (cyclopropane, halogenated hydrocarbons) · Increased risk of developing arrhythmias. Propranolol may be administered should these occur.
• Beta-Blockers · May antagonize isoproterenol's cardiac, bronchodilating, and vasodilating effects. Can be used to treat isoproterenol-induced tachycardia, but use with caution in bronchospastic disease.
• Digoxin (Digitalis glycosides) · Increased risk of arrhythmias.
• Oxytocic Agents · Hypertension may result if used concurrently.
• Other Sympathomimetic Agents (e.g., phenylpropanolamine) · Should not be administered concurrently as increased toxicity may result.
• Theophylline · May increase the risk for theophylline toxicity.

모니터링

• Cardiac rate and rhythm (ECG continuous monitoring highly recommended)
• Respiratory rate and auscultation (especially during anaphylaxis)
• Blood pressure
• Blood gases (if indicated and possible)
• Urine flow (if possible)

과용량

High doses may cause an initial **hypertension**, followed by **hypotension**, as well as severe **tachycardias and other arrhythmias**. **Treatment:** * Halt or reduce the drug infusion (effects dissipate rapidly due to short half-life). * Provide supportive care. * If tachycardias persist, a **beta-blocker** could be considered for treatment, provided the patient does not have a bronchospastic disease.