수산화마그네슘

동물 종별 용량

용량은 면허 수의 전문가를 위한 임상 참고 자료입니다. 항상 최신 라벨과 개별 환자에 대해 확인하십시오.

투여 경로

금기

• Renal disease (due to risk of hypermagnesemia)
• Gastric outlet obstruction (for aluminum-containing products)
• Use cautiously in patients on sodium- or potassium-restricted diets (some products contain significant amounts)

이상반응

• Diarrhea or frequent loose stools
• Hypermagnesemia (especially in patients with severe renal insufficiency)
• Constipation (if using combination products with aluminum)
• Hypophosphatemia (with chronic use of aluminum-containing products)

약물 상호작용

• Quinidine · Increased absorption or pharmacologic effect may occur
• Sodium Polystyrene Sulfonate · May decrease the potassium-lowering effectiveness; may cause metabolic alkalosis in renal failure patients
• Sustained-release medications · May alter absorption by changing GI transit times when used at laxative dosages
• Sympathomimetic agents · Increased absorption or pharmacologic effect may occur
• Fluoroquinolones · Decreased absorption (chelation); separate doses by at least 2 hours
• Tetracyclines · Decreased absorption (chelation); separate doses by at least 2 hours
• Azole Antifungals (Ketoconazole, Itraconazole) · Decreased absorption due to increased gastric pH; separate doses by at least 2 hours
• Digoxin · Decreased absorption; separate doses by at least 2 hours
• Iron Salts · Decreased absorption; separate doses by at least 2 hours
• H-2 Antagonists · Decreased absorption; separate doses by at least 2 hours
• Thyroid Hormones · Decreased absorption; separate doses by at least 2 hours
• Corticosteroids · Decreased absorption; separate doses by at least 2 hours

모니터링

• Electrolyte imbalances (Magnesium, Phosphorus, Calcium) with chronic or high-dose therapy
• Renal function
• Fecal consistency

과용량

Chronic or acute overdose can lead to significant GI upset (severe diarrhea) and electrolyte imbalances (hypermagnesemia, especially in renal failure). Treat symptomatically with fluid therapy and correct electrolyte derangements.