중쇄 중성지방 (MCT 오일)

영양 보충제 / 지질

중쇄 중성지방(MCT)은 소장의 만성 침윤성 질환이나 지방 흡수 불량 증후군으로 인해 지방 섭취가 제한된 개에게 칼로리를 제공하기 위해 사용되는 지질 보충제입니다. 고양이의 경우 경구 약물 투여를 위한 기제로 사용되기도 합니다.

작용 기전: MCTs bypass the traditional, complex lipid digestion and absorption pathways required by long-chain triglycerides (LCTs): **Triglycerides** → hydrolyzed by **gastric and pancreatic lipases** (requires significantly less bile acids than LCTs) → **Medium-chain fatty acids (MCFAs)** → absorbed directly into enterocytes → enter the **portal vein** directly (bypassing **chylomicron** formation and **lymphatic transport**) → rapid oxidation in the liver for immediate energy. Because they do not rely on the lymphatic system, they are ideal for patients with lymphatic obstruction or dilation (e.g., lymphangiectasia).

동물 종별 용량

Cats

Base-vehicle to administer drugs · 0.1 mL/kg · PO · as needed · Owner-perceived acceptability by cats of MCT oil was significantly higher than gelatin capsules.

Dogs

To offset caloric reduction when long-chain triglycerides are restricted · ½-4 teaspoons divided per day with food · PO · divided daily
To offset caloric reduction when long-chain triglycerides are restricted · 0.5-2 mL/kg per day added to food · PO · daily
To offset caloric reduction when long-chain triglycerides are restricted · 1-2 mL/kg per day · PO · daily

용량은 면허 수의 전문가를 위한 임상 참고 자료입니다. 항상 최신 라벨과 개별 환자에 대해 확인하십시오.

투여 경로

금기

Significant hepatic disease (e.g., portosystemic shunts, cirrhosis, hepatic failure)

이상반응

Unpalatability (especially in dogs)
Bloating
Flatulence
Diarrhea
Food aversion (rare in cats)

약물 상호작용

Griseofulvin · MCT oil may decrease absorption, as griseofulvin requires long-chain dietary fats for optimal oral absorption.
Fat-soluble vitamins (A, D, E, K) · Absorption may be impaired if LCTs are completely replaced by MCTs; supplementation may be required.

모니터링

Gastrointestinal tolerance (vomiting, bloating, flatulence, stool consistency)
Efficacy (maintenance of body weight and body condition score)
Signs of hepatic encephalopathy in patients with underlying liver disease

과용량

Overdosage primarily exacerbates gastrointestinal adverse effects, leading to **bloating, flatulence, and severe diarrhea**. **Treatment:** * Discontinue or reduce the dose of MCT oil. * Treat severe diarrhea supportively (e.g., fluid therapy to correct dehydration and electrolyte imbalances) if necessary.

VetSheet 약물 레퍼런스는 면허 수의 전문가를 위한 임상 의사결정 보조 도구이며, 전문적 판단이나 제조사의 최신 라벨을 대신하지 않습니다.