μμ°νμ§μ (μμκ°μ€)
μμ°νμ§μ(N2O)λ μ΄μν루λκ³Ό κ°μ νλ°μ± λ§μ·¨μ μ μ λ λ° μ μ§λ₯Ό λκΈ° μν΄ μ°μμ ν¨κ» μ¬μ©λλ ν‘μ κ°μ€μ λλ€. μ£Όμ ν‘μ λ§μ·¨μ μ νμ λλλ₯Ό μ€μ¬μ£Όλ©°, **μ 2κ°μ€ ν¨κ³Ό(second gas effect)** λ° **λλ ν¨κ³Ό(concentration effect)**λ₯Ό ν΅ν΄ μμ μ μΈ λ§μ·¨ μνμ λ 빨리 λλ¬νκ² ν©λλ€. > **μμ κ²½κ³ :** N2Oλ 체λ΄μ κ°μ€κ° μ°¬ 곡κ°μ λΉ λ₯΄κ² ν½μ°½μμΌ λΆνΌλ μλ ₯μ μ¦κ°μν΅λλ€. κΈ°νμ΄λ μνμ₯ κΌ¬μ(GDV) νμμκ²λ μ λ κΈκΈ°μ λλ€. > **μμ κ²½κ³ :** N2O ν¬μ¬λ₯Ό μ€λ¨ν νμλ **νμ°μ± μ μ°μμ¦(diffusion hypoxia)**μ μλ°©νκΈ° μν΄ 5~10λΆ λμ μ°μλ₯Ό 곡κΈν΄μΌ ν©λλ€.
μμ© κΈ°μ : Nitrous oxide causes generalized **CNS depression**. When administered at the beginning of volatile agent anaesthesia, it increases the speed of uptake of the volatile agent from the alveoli β **second gas effect** and **concentration effect** β hastens attainment of a stable plane of anaesthesia. It has minimal direct respiratory and cardiovascular effects.
λλ¬Ό μ’ λ³ μ©λ
- Adjunct for induction and maintenance of anaesthesia Β· Inspired concentrations of 50-70% Β· Inhalational Β· Continuous during anaesthesia Β· Duration of procedure Β· Must be administered with a minimum of 30% oxygen.
- Adjunct for induction and maintenance of anaesthesia Β· Inspired concentrations of 50-70% Β· Inhalational Β· Continuous during anaesthesia Β· Duration of procedure Β· Must be administered with a minimum of 30% oxygen.
μ©λμ λ©΄ν μμ μ λ¬Έκ°λ₯Ό μν μμ μ°Έκ³ μλ£μ λλ€. νμ μ΅μ λΌλ²¨κ³Ό κ°λ³ νμμ λν΄ νμΈνμμμ€.
ν¬μ¬ κ²½λ‘
κΈκΈ°
- Patients with air-filled spaces within the body (e.g., pneumothorax, gastric dilatation/GDV, intestinal obstruction)
- Marked respiratory compromise (due to hypoxia risks)
- Raised intracranial pressure (due to associated increases in cerebral blood flow)
μ΄μλ°μ
- Diffusion hypoxia (if oxygen is not supplemented upon discontinuation)
- Megaloblastic changes in bone marrow (with exposure lasting a few hours)
- Agranulocytosis (with prolonged exposure of a few days)
λͺ¨λν°λ§
- Inspired oxygen concentration (FiO2) - especially in rebreathing circuits
- Pulse oximetry (SpO2)
- Capnography (ETCO2)
- Respiratory rate and effort
- Cardiovascular parameters (HR, BP)
κ³Όμ©λ
Overdosage primarily presents as **hypoxia** if the inspired oxygen concentration falls below 30%. Treatment consists of immediately discontinuing nitrous oxide and providing 100% oxygen via positive pressure ventilation if necessary.
VetSheet μ½λ¬Ό λ νΌλ°μ€λ λ©΄ν μμ μ λ¬Έκ°λ₯Ό μν μμ μμ¬κ²°μ 보쑰 λꡬμ΄λ©°, μ λ¬Έμ νλ¨μ΄λ μ μ‘°μ¬μ μ΅μ λΌλ²¨μ λμ νμ§ μμ΅λλ€.