λμ€νν΄
λμ€νν΄μ κ΄λ²μ **ν΄λ¦¬μκ³ νμ§κ· μ **λ‘, νΉν **μΉΈλλ€**(νΉν *C. albicans*)μ λν ν¨λ₯μ΄ λ°μ΄λ©λλ€. μμ₯κ΄μμ ν‘μλμ§ μμΌλ―λ‘ κ΅μ/μΈμ© λλ μμ₯κ΄ μ§κ· κ°μΌμ μ ν©ν©λλ€. > **μμ ν:** μ μ μΌλ‘ ν‘μλμ§ μκΈ° λλ¬Έμ κ²½κ΅¬μ© μ μ λ μμ₯κ΄ μΉΈλλ€μ¦μλ§ ν¨κ³Όκ° μμΌλ©°, κ΅μμ© μ μ λ νΌλΆλ κ·μ ν¨λͺ¨ κ°μΌ(μ: λ§λΌμΈμ§μ μΈμ΄μΌ)μ μ¬μ©λ©λλ€.
μμ© κΈ°μ : Nystatin binds to **ergosterol**, a major component of the fungal cell membrane. This binding β forms pores in the membrane β leads to **potassium leakage** β results in the death of the fungus.
λλ¬Ό μ’ λ³ μ©λ
- Topical antifungal therapy Β· apply to affected areas Β· topical Β· q8-12h Β· Until clinical resolution Β· Often used for otitis externa or localized cutaneous candidiasis/malassezia.
- Topical antifungal therapy Β· apply to affected areas Β· topical Β· q8-12h Β· Until clinical resolution Β· Often used for otitis externa or localized cutaneous candidiasis/malassezia.
μ©λμ λ©΄ν μμ μ λ¬Έκ°λ₯Ό μν μμ μ°Έκ³ μλ£μ λλ€. νμ μ΅μ λΌλ²¨κ³Ό κ°λ³ νμμ λν΄ νμΈνμμμ€.
ν¬μ¬ κ²½λ‘
κΈκΈ°
- Known hypersensitivity to nystatin
μ΄μλ°μ
- Generally well tolerated due to lack of systemic absorption
- Rarely GI upset if given orally (nausea, vomiting, diarrhea)
- Mild irritation or hypersensitivity at the site of topical application (rare)
λͺ¨λν°λ§
- Resolution of clinical signs of fungal/yeast infection
- Skin/ear cytology to confirm clearance of Malassezia or Candida
κ³Όμ©λ
Overdose is highly unlikely to cause systemic toxicity due to the lack of gastrointestinal absorption. Massive oral overdose may cause mild gastrointestinal distress (vomiting, diarrhea).
VetSheet μ½λ¬Ό λ νΌλ°μ€λ λ©΄ν μμ μ λ¬Έκ°λ₯Ό μν μμ μμ¬κ²°μ 보쑰 λꡬμ΄λ©°, μ λ¬Έμ νλ¨μ΄λ μ μ‘°μ¬μ μ΅μ λΌλ²¨μ λμ νμ§ μμ΅λλ€.