ννλ² λ νΌ
ννλ² λ νΌμ 무μ λͺ¨λ₯΄ν 85.5%, 무μ μ½λ°μΈ 6.8%, ννλ² λ¦° 7.8%μ ν΄λΉνλ μ±λΆμ ν¬ν¨νλ μνΈ μμΉΌλ‘μ΄λ νΌν©λ¬Όμ λλ€. μμ μ νμ μ€λ±λμμ μ€μ¦ ν΅μ¦ κ΄λ¦¬μ μ¬μ©λλ©°, λ λμ μ§μ λ° μ§ν΅ ν¨κ³Όλ₯Ό μ 곡νκΈ° μν΄ μ§μ λ° λ§μ·¨ μ ν¬μ½ νλ‘ν μ½μ ν¬ν¨λ©λλ€. λͺ¨λ₯΄νκ³Ό μ μ¬ν ν¨κ³Όλ₯Ό κ°μ§λ©° μμ© μκ°μ μ½ 4μκ°μ λλ€. > **μμ κ²½κ³ :** κ°μ κ³ μμ΄μκ² λ¨ν λλ λ°λ³΅ λ³Όλ£¨μ€ ν¬μ¬ μ νκ°λ λ체μ μΈ λ©νλμ ννλ² λ νΌλ³΄λ€ μ°μ μ μΌλ‘ μ¬μ©ν΄μΌ ν©λλ€. ννλ² λ νΌμ μμ ν μ§ν΅μ λ‘ λ리 μ¬μ©λμ§λ μμ§λ§, 곡격μ μΈ κ°μκ² μ’μ μ§μ ν¨κ³Όλ₯Ό μ 곡νκΈ° μν΄ μμΈνλ‘λ§μ§κ³Ό ν¨κ» μ¬μ©λλ κ²½ν₯μ΄ μμ΅λλ€.
μμ© κΈ°μ : Papaveretum provides analgesia primarily mediated by acting as an agonist at the **mu (ΞΌ) opioid receptor** in the central nervous system. This binding inhibits the release of nociceptive neurotransmitters (such as Substance P) β altering the perception of and response to pain.
λλ¬Ό μ’ λ³ μ©λ
- Analgesia / Sedation Β· 0.2-0.8 mg/kg Β· IV/IM/SC Β· PRN Β· Duration of action is approximately 4 hours Β· Use lower doses IV; only use higher doses when deep sedation is required. Often given as part of a combination for sedation.
- Analgesia / Sedation Β· 0.2-0.3 mg/kg Β· IV/IM/SC Β· PRN Β· Duration of action is approximately 4 hours Β· Often given as part of a combination for sedation.
μ©λμ λ©΄ν μμ μ λ¬Έκ°λ₯Ό μν μμ μ°Έκ³ μλ£μ λλ€. νμ μ΅μ λΌλ²¨κ³Ό κ°λ³ νμμ λν΄ νμΈνμμμ€.
ν¬μ¬ κ²½λ‘
κΈκΈ°
- No specific contraindications available, but use with caution in patients with impaired liver function or pregnant animals near parturition.
μ΄μλ°μ
- Vomiting (common)
- Respiratory depression (especially IV during general anaesthesia)
- Constriction of gastrointestinal sphincters (e.g., pyloric sphincter)
- Reduction in gastrointestinal motility
- Sedation in neonates (crosses placenta)
μ½λ¬Ό μνΈμμ©
- Anaesthetics Β· Increased CNS or respiratory depression Β· major
- Antihistamines Β· Increased CNS or respiratory depression Β· moderate
- Barbiturates Β· Increased CNS or respiratory depression Β· major
- Phenothiazines (e.g., Acepromazine) Β· Increased CNS or respiratory depression; often used together intentionally for deep sedation Β· moderate
- Tranquillizers Β· Increased CNS or respiratory depression Β· moderate
λͺ¨λν°λ§
- Respiratory rate and depth (especially under general anaesthesia)
- Pain scores (due to variable individual response)
- Level of sedation
- Heart rate and blood pressure
κ³Όμ©λ
Overdose can lead to severe **respiratory depression**, profound sedation, and potentially cardiovascular collapse. Severe adverse effects can be treated and reversed with the opioid antagonist **naloxone**.
VetSheet μ½λ¬Ό λ νΌλ°μ€λ λ©΄ν μμ μ λ¬Έκ°λ₯Ό μν μμ μμ¬κ²°μ 보쑰 λꡬμ΄λ©°, μ λ¬Έμ νλ¨μ΄λ μ μ‘°μ¬μ μ΅μ λΌλ²¨μ λμ νμ§ μμ΅λλ€.