프라도플록사신

동물 종별 용량

용량은 면허 수의 전문가를 위한 임상 참고 자료입니다. 항상 최신 라벨과 개별 환자에 대해 확인하십시오.

투여 경로

금기

• Pregnant or lactating animals
• Dogs < 12 months of age (< 18 months for giant breeds)
• Cats < 6 weeks of age
• Animals with persistent cartilage lesions
• Dogs or cats with neurological disease (especially epilepsy)

이상반응

• Mild gastrointestinal upset (vomiting, diarrhea, anorexia)

약물 상호작용

• Antacids (Mg2+, Al3+) · Binds fluoroquinolones, preventing absorption from the GI tract · major
• Sucralfate · Inhibits absorption; separate dosing by at least 2 hours · major
• Zinc salts · Inhibits absorption; separate dosing by at least 2 hours · moderate
• Theophylline · Increases plasma theophylline concentrations · major
• Cimetidine · May reduce the clearance of fluoroquinolones · moderate
• Ciclosporin · May decrease metabolism and increase nephrotoxicity; concurrent use best avoided · major
• Tacrolimus · May decrease metabolism and increase nephrotoxicity; concurrent use best avoided · major
• Oral anticoagulants · May increase the action of orally administered anticoagulants · moderate

모니터링

• Clinical efficacy (resolution of infection)
• Gastrointestinal signs
• Neurological status (especially in predisposed animals)

과용량

Overdose may increase the risk of gastrointestinal upset, neurological signs (tremors, seizures), and cartilage damage in growing animals. Treatment is symptomatic and supportive. Emptying the stomach and administering activated charcoal may be beneficial if ingestion was recent.