셀라멕틴

동물 종별 용량

투여 경로

금기

• Application to broken skin
• Application to wet hair coats
• Use in severely debilitated or underweight animals (relative)
• Puppies and kittens under 6 weeks of age
• Sick, debilitated, or severely underweight animals
• Known hypersensitivity to the active substance or excipients

이상반응

• Transient localized alopecia at application site (rare)
• Mild, transient gastrointestinal signs (vomiting, diarrhea) if ingested
• Transient local alopecia at the application site
• Application site irritation or pruritus
• Rarely: vomiting, diarrhea, lethargy, or anorexia
• Rarely: neurological signs (tremors, ataxia) in highly sensitive individuals

약물 상호작용

• Other macrocyclic lactones (e.g., ivermectin, milbemycin) · Potential for additive toxicity, though selamectin has a high margin of safety. · minor
• P-glycoprotein inhibitors (e.g., ketoconazole, cyclosporine) · May theoretically increase systemic absorption and CNS penetration, increasing the risk of toxicity. · moderate

모니터링

• Clinical efficacy
• Owner compliance with treatment regimen
• Efficacy of parasite control
• Application site for signs of irritation or alopecia

과용량

Generally very safe. Overdoses up to 10 times the recommended dose typically do not produce clinical signs in dogs or cats. If massive accidental ingestion occurs, monitor for neurologic signs (ataxia, tremors, mydriasis) and provide supportive care.