소마토트로핀 / 성장 호르몬

동물 종별 용량

용량은 면허 수의 전문가를 위한 임상 참고 자료입니다. 항상 최신 라벨과 개별 환자에 대해 확인하십시오.

투여 경로

금기

• Closed epiphyseal plates (if seeking linear growth)
• Neoplasia (may stimulate tumor growth)
• Diabetes mellitus
• Hypersensitivity to the drug or formulation components
• Patients with closed epiphyses (unless treating specific adult-onset deficiencies)
• Known hypersensitivity
• Active neoplasia

이상반응

• Hyperglycemia
• Insulin resistance / Diabetes mellitus
• Acromegaly (with prolonged use)
• Antibody formation (when using human GH in pets)
• Injection site reactions
• Diabetogenic effect (hyperglycemia/diabetes mellitus)
• Local injection site reactions
• Antibody formation (reducing long-term efficacy)

약물 상호작용

• Glucocorticoids · May antagonize the growth-promoting effects of somatotropin. · moderate
• Insulin · Somatotropin induces insulin resistance, potentially requiring significant adjustments in insulin dosage for diabetic patients. · major

모니터링

• Serum IGF-1 levels
• Blood glucose and urine glucose
• Thyroid panel (TSH/T4)
• Growth rate and body weight
• Physical signs of acromegaly
• Blood glucose
• Growth rate/body weight
• Injection site reactions

과용량

Acute overdose is unlikely to cause severe clinical signs other than transient hypoglycemia followed by hyperglycemia. Chronic overdosage leads to **acromegaly** and **diabetes mellitus**.