수펜타닐

동물 종별 용량

용량은 면허 수의 전문가를 위한 임상 참고 자료입니다. 항상 최신 라벨과 개별 환자에 대해 확인하십시오.

투여 경로

금기

• Hypersensitivity to sufentanil or other opioids

이상반응

• Respiratory depression (dose-related)
• CNS depression
• Bradycardia
• Skeletal muscle rigidity
• Asystole (rare)
• Hypercarbia (rare)
• Hypersensitivity reactions (rare)

약물 상호작용

• Beta-adrenergic blockers · May increase bradycardia and hypotension
• Calcium-channel blockers · May increase bradycardia and hypotension
• CNS depressants (e.g., barbiturates) · Additive effects can occur, exacerbating CNS or respiratory depression
• Nitrous oxide · Can cause cardiovascular depression if used with high dose sufentanil

모니터링

• Anesthetic and/or analgesic efficacy
• Cardiac rate
• Respiratory rate
• Pulse oximetry or other methods to measure blood oxygenation

과용량

In dogs, the LD50 of intravenous sufentanil is 10.1-19.5 mg/kg. **Clinical Signs of Severe Overdose:** * Apnea * Circulatory collapse * Pulmonary edema * Seizures * Cardiac arrest and death **Treatment:** Consists of a combination of supportive therapy (ventilation, cardiovascular support) and administration of an opiate antagonist such as **naloxone**. Although sufentanil has a fairly rapid half-life, multiple doses of naloxone may be necessary. > **Clinical Pearl:** Because of the drug's extreme potency, use a tuberculin syringe to measure dosages less than 1 mL, and employ a dosage calculation/measurement double-check system.