ํธ๋กํผ์นด๋ง์ด๋
ํธ๋กํผ์นด๋ง์ด๋๋ ์ฐ๋ ๋ฐ ์ฌ๋ชจ์ฒด๊ทผ ๋ง๋น์ ์ฌ์ฉ๋๋ ํฉ์ฑ ๋จ๊ธฐ ์์ฉ ํญ์ฝ๋ฆฐ์ ์ ๋๋ค. ์์ฉ ๋ฐํ์ด ๋น ๋ฅด๊ณ (20-30๋ถ) ์์ฉ ์๊ฐ์ด ์งง์ ์๊ตฌ ๋ด ๊ฒ์ฌ๋ฅผ ์ํ 1์ฐจ ์ ํ ์ฐ๋์ ์ ๋๋ค. > **์์ ํ:** ์ฌ๋ชจ์ฒด๊ทผ ๋ง๋น ํจ๊ณผ๋ณด๋ค ์ฐ๋ ํจ๊ณผ๊ฐ ๋ ๋ฐ์ด๋๋ฏ๋ก ํฌ๋๋ง์ผ๊ณผ ๊ด๋ จ๋ ์ฌ๋ชจ์ฒด๊ทผ ๊ฒฝ๋ จ ์ํ์๋ ์ํธ๋กํ๋ณด๋ค ํจ๊ณผ๊ฐ ๋จ์ด์ง๋๋ค.
์์ฉ ๊ธฐ์ : Tropicamide acts as a competitive antagonist of acetylcholine at muscarinic receptors. **Acetylcholine inhibition** at the iris sphincter muscle โ relaxation of the sphincter โ **mydriasis** (pupil dilation). **Acetylcholine inhibition** at the ciliary body muscles โ paralysis of accommodation โ **cycloplegia**.
๋๋ฌผ ์ข ๋ณ ์ฉ๋
- Mydriasis and cycloplegia for intraocular examination ยท 1 drop per eye ยท topical ยท repeat after 20-30 min if necessary ยท Duration of action is 2-12 hours.
- Mydriasis and cycloplegia for intraocular examination ยท 1 drop per eye ยท topical ยท repeat after 20-30 min if necessary ยท Duration of action is 4-9 hours. May cause salivation.
์ฉ๋์ ๋ฉดํ ์์ ์ ๋ฌธ๊ฐ๋ฅผ ์ํ ์์ ์ฐธ๊ณ ์๋ฃ์ ๋๋ค. ํญ์ ์ต์ ๋ผ๋ฒจ๊ณผ ๊ฐ๋ณ ํ์์ ๋ํด ํ์ธํ์ญ์์ค.
ํฌ์ฌ ๊ฒฝ๋ก
๊ธ๊ธฐ
- Glaucoma (may increase intraocular pressure)
์ด์๋ฐ์
- Salivation (particularly in cats, though less marked than with atropine)
- Transient stinging upon application
- Photophobia (due to pupil dilation)
๋ชจ๋ํฐ๋ง
- Intraocular pressure (IOP)
- Pupillary light reflex
- Resolution of mydriasis
๊ณผ์ฉ๋
Systemic toxicity is rare with standard topical ophthalmic use. However, excessive administration or ingestion could theoretically lead to systemic anticholinergic signs such as **tachycardia**, **dry mucous membranes**, **ileus**, and **urinary retention**. Treatment is generally supportive.
VetSheet ์ฝ๋ฌผ ๋ ํผ๋ฐ์ค๋ ๋ฉดํ ์์ ์ ๋ฌธ๊ฐ๋ฅผ ์ํ ์์ ์์ฌ๊ฒฐ์ ๋ณด์กฐ ๋๊ตฌ์ด๋ฉฐ, ์ ๋ฌธ์ ํ๋จ์ด๋ ์ ์กฐ์ฌ์ ์ต์ ๋ผ๋ฒจ์ ๋์ ํ์ง ์์ต๋๋ค.