졸라제팜 및 틸레타민

동물 종별 용량

용량은 면허 수의 전문가를 위한 임상 참고 자료입니다. 항상 최신 라벨과 개별 환자에 대해 확인하십시오.

투여 경로

금기

• Severe cardiac disease
• Severe respiratory disease
• Hypertensive disease
• Renal insufficiency
• Pancreatic insufficiency
• Hepatic insufficiency
• Head trauma or intracranial tumours
• Pregnancy (crosses the placenta and causes fatal respiratory depression in neonates)

이상반응

• Excessive salivation (ptyalism)
• Muscle rigidity during recovery
• Prolonged and excitable recovery (especially in dogs at higher doses)
• Pain on intramuscular injection (particularly in cats)
• Respiratory depression (can be fatal in neonates)
• Hypothermia

약물 상호작용

• Phenothiazines (e.g., Acepromazine) · Increased cardiorespiratory depression and increased hypothermic effect during the last phase of anesthesia. · major
• Chloramphenicol · Slows down the elimination of the anesthetics if used during the pre- or intraoperative period. · moderate

모니터링

• Heart rate and rhythm
• Respiratory rate and depth
• Body temperature (monitor closely for hypothermia)
• Depth of anesthesia (jaw tone, palpebral reflex)
• Quality of recovery (monitor for excitation or rigidity)

과용량

Overdosage increases the risk of severe **cardiorespiratory depression**, prolonged anesthesia, and highly excitable or rough recoveries. Treatment is supportive, including mechanical ventilation if respiratory failure occurs, thermal support for hypothermia, and potentially benzodiazepine antagonists (flumazenil) for the zolazepam component, though this leaves the tiletamine unopposed.