Paraffin

Paraffin (also known as liquid paraffin or mineral oil) is a widely used **lubricant laxative** and **ophthalmic tear substitute** in veterinary medicine. Orally, it is used to manage constipation and hairballs (especially in cats). Topically, it is used to lubricate the eyes and prevent tear evaporation. > **Clinical Pearl:** Extreme caution must be used when administering liquid paraffin orally due to the severe risk of **aspiration pneumonia**. It is tasteless and does not elicit a normal gag reflex, making aspiration highly likely if force-fed.

กลไกการออกฤทธิ์: Paraffin has two distinct mechanisms depending on the route of administration: * **Gastrointestinal (Laxative):** Acts as an emollient laxative. It coats the feces and intestinal mucosa → interferes with intestinal water resorption → softens stools and facilitates passage. * **Ophthalmic (Lubricant):** Acts as a lipid-based tear substitute. It mimics the **lipid layer** of the tear film → prevents aqueous tear evaporation and protects the corneal surface.

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