α-酪蛋白肽
營養保健品 / 抗焦慮劑
α-酪蛋白肽是一種源自牛奶蛋白的**類苯二氮平十肽**。它被用作鎮靜營養保健品,以減少狗和貓面臨各種壓力源(如寄宿、不可預測的情況或環境改變,例如新生兒到來)時的影響。 > **臨床警告:** 最近的文獻回顧指出,支持使用 α-酪蛋白肽治療焦慮症的證據較弱。建議將其作為環境管理與綜合行為矯正計畫的輔助手段,而非單一療法。
作用機制: Acts as a **GABA-B agonist**. It mimics the properties of benzodiazepines by binding to GABA receptors in the central nervous system → promoting inhibitory neurotransmission → resulting in a mild calming or anxiolytic effect without significant sedation or muscle relaxation.
各物種劑量
Dogs
- Stress and anxiety reduction · 15 mg/kg · PO · q24h · Start before exposure to stressor · Evidence for efficacy is considered weak.
Cats
- Stress and anxiety reduction · 15 mg/kg · PO · q24h · Start before exposure to stressor
劑量為持牌獸醫專業人員的臨床參考。請務必對照最新藥品說明書及個別病患確認。
給藥途徑
PO
禁忌症
- None reported
不良反應
- Diarrhea (occasional)
監測
- Clinical response to the stressor
- Fecal consistency (monitor for diarrhea)
過量
No specific overdosage information is provided. As a milk-derived nutraceutical, it has a very wide margin of safety. Massive overdose may lead to gastrointestinal upset (diarrhea).
VetSheet 藥物參考供持牌獸醫專業人員作臨床決策輔助之用,不能取代專業判斷或廠方最新藥品說明書。