卡波姆 980
Carbomer 980
Polyacrylic acid
別名: Lubrithal · Ocry-gel · OptixCare · Viscotears · Polyacrylic acid · Carboxy polymethylene
由 VetSheet 獸醫團隊審訂更新於 2026年4月5日本內容以實證獸醫文獻為本
劑量為持牌獸醫專業人員的臨床參考。請務必對照最新藥品說明書及個別病患確認。
各物種劑量
🌎 NA — North America🌍 EU — Europe
狗
| 適應症 | 劑量 | 途徑 | 頻次 | 療程 | 地區 |
|---|---|---|---|---|---|
| Keratoconjunctivitis sicca (KCS) / Dry eye / Ocular lubrication | 1 drop (or small strip) per affected eye | topical | prn (typically q6h to q12h) | Ongoing | 🌍 EU |
| Corneal protection during general anesthesia | 1 drop (or small strip) per eye | topical | Once after induction, repeat every 1-2 hours if procedure is prolonged | Duration of anesthesia | 🌍 EU |
- Keratoconjunctivitis sicca (KCS) / Dry eye / Ocular lubrication: Frequency depends on the severity of the dry eye.
- Corneal protection during general anesthesia: Prevents exposure keratitis.
貓
| 適應症 | 劑量 | 途徑 | 頻次 | 療程 | 地區 |
|---|---|---|---|---|---|
| Keratoconjunctivitis sicca (KCS) / Dry eye / Ocular lubrication | 1 drop (or small strip) per affected eye | topical | prn (typically q6h to q12h) | Ongoing | 🌍 EU |
| Corneal protection during general anesthesia | 1 drop (or small strip) per eye | topical | Once after induction, repeat every 1-2 hours if procedure is prolonged | Duration of anesthesia | 🌍 EU |
- Keratoconjunctivitis sicca (KCS) / Dry eye / Ocular lubrication: Frequency depends on the severity of the dry eye.
- Corneal protection during general anesthesia: Prevents exposure keratitis.
小型哺乳類
| 適應症 | 劑量 | 途徑 | 頻次 | 療程 | 地區 |
|---|---|---|---|---|---|
| Ocular lubrication / Anesthesia protection | 1 drop per eye | topical | prn | As needed | 🌍 EU |
- Ocular lubrication / Anesthesia protection: Useful for exophthalmic species (e.g., rabbits, guinea pigs) during anesthesia.
劑量為持牌獸醫專業人員的臨床參考。請務必對照最新藥品說明書及個別病患確認。
概覽
卡波姆 980 是一種合成的高分子量聚丙烯酸交聯聚合物，用作眼科潤滑劑。它具有仿黏蛋白作用，可替代三層淚膜的水層和黏蛋白層。
臨床提示： 卡波姆凝膠對於治療乾眼症（KCS）以及在全身麻醉或鎮靜期間（當眼瞼反射減弱或消失時）提供必要的角膜保護非常有效。
作用機制
Carbomer 980 is a linear polymer (polyacrylic acid) that acts as a mucinomimetic. It adheres to the corneal surface and retains moisture → replaces the aqueous and mucin layers of the trilaminar tear film → stabilizes the tear film, reduces tear evaporation, and prolongs tear break-up time (TBUT).
安全性與警告
禁忌症
- Hypersensitivity to carbomer or any component of the formulation (e.g., preservatives like cetrimide or benzalkonium chloride)
不良反應
- Transient blurred vision immediately after application
- Mild, temporary ocular irritation or stinging
- Crusting or matting of the eyelashes/eyelids
注意事項
Application Order: When using multiple eye medications, always apply aqueous drops first, wait 5-10 minutes, and apply carbomer gel last.
- Avoid touching the tip of the tube to the eye, eyelids, or fingers to prevent contamination.
- Some human formulations contain preservatives that may cause irritation with very frequent, long-term use; preservative-free single-use vials are preferred for severe KCS requiring highly frequent application.
藥物相互作用
Carbomer gel can act as a physical barrier, reducing the absorption of other ophthalmic drops if applied simultaneously or prior to the drops.
監測
- Schirmer Tear Test (STT) to monitor tear production in KCS patients
- Resolution of clinical signs (conjunctival hyperemia, mucoid discharge, blepharospasm)
- Fluorescein staining to monitor for corneal ulceration
藥物動力學
半衰期
吸收
Not absorbed systemically. Remains on the ocular surface.
分佈
Distributes evenly across the cornea and conjunctiva, mixing with the natural tear film.
代謝
Not metabolized.
排除
Cleared from the eye via the nasolacrimal duct and normal tear turnover.
過量
Overdosage is not a clinical concern due to the lack of systemic absorption. Excess gel will simply spill over the eyelid margins and can be gently wiped away with a damp tissue.
可用產品
劑型
- Ophthalmic gel: 0.2% (10 g tube, single-use vial)
- Ophthalmic gel: 0.25% (10 g tube)
獸醫用
- Lubrithal 0.2% eye gel
- Ocry-gel
- OptixCare Eye Lube
人用標示
- Viscotears 0.2% liquid gel
各地核准狀態
Available Over-The-Counter (OTC) as artificial tears.
Available as Pharmacy (P) or General Sale depending on the specific product.
Available as Pharmacy (P) or General Sale depending on the specific product.
暫無法規資料: 🇭🇰 HK · 🇹🇼 TW · 🇯🇵 JP · 🇰🇷 KR · 🇦🇺 AU
儲存與穩定性
Store at room temperature (below 25°C). Do not freeze. Discard the tube 28 days after opening (or as directed by the manufacturer) to prevent microbial contamination. Single-use vials should be discarded immediately after use.
飼主須知
- 給藥方法： 點眼藥前請先洗手。輕輕拉下下眼瞼，將一小滴或一小條凝膠擠入眼袋中。
- 衛生： 切勿讓管口接觸到寵物的眼睛、眼瞼或您的手指。
- 多種藥物： 如果您的寵物需要使用其他眼藥水，請先點水性眼藥水，等待至少 5 到 10 分鐘後，最後再塗抹此凝膠。
- 副作用： 點藥後幾分鐘內，寵物的視力可能會稍微模糊。您也可能會注意到睫毛周圍有一些結痂，可以用溫暖的濕布輕輕擦拭乾淨。
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