卡波姆 980
眼科潤滑劑 / 人工淚液
卡波姆 980 是一種合成的高分子量聚丙烯酸交聯聚合物，用作眼科潤滑劑。它具有仿黏蛋白作用，可替代三層淚膜的水層和黏蛋白層。 **臨床提示：** 卡波姆凝膠對於治療乾眼症（KCS）以及在全身麻醉或鎮靜期間（當眼瞼反射減弱或消失時）提供必要的角膜保護非常有效。
作用機制: **Carbomer 980** is a linear polymer (**polyacrylic acid**) that acts as a **mucinomimetic**. It adheres to the corneal surface and retains moisture → replaces the aqueous and mucin layers of the trilaminar tear film → stabilizes the tear film, reduces tear evaporation, and prolongs tear break-up time (TBUT).
各物種劑量
Cats
- Keratoconjunctivitis sicca (KCS) / Dry eye / Ocular lubrication · 1 drop (or small strip) per affected eye · topical · prn (typically q6h to q12h) · Ongoing · Frequency depends on the severity of the dry eye.
- Corneal protection during general anesthesia · 1 drop (or small strip) per eye · topical · Once after induction, repeat every 1-2 hours if procedure is prolonged · Duration of anesthesia · Prevents exposure keratitis.
Dogs
- Keratoconjunctivitis sicca (KCS) / Dry eye / Ocular lubrication · 1 drop (or small strip) per affected eye · topical · prn (typically q6h to q12h) · Ongoing · Frequency depends on the severity of the dry eye.
- Corneal protection during general anesthesia · 1 drop (or small strip) per eye · topical · Once after induction, repeat every 1-2 hours if procedure is prolonged · Duration of anesthesia · Prevents exposure keratitis.
SmallMammals
- Ocular lubrication / Anesthesia protection · 1 drop per eye · topical · prn · As needed · Useful for exophthalmic species (e.g., rabbits, guinea pigs) during anesthesia.
劑量為持牌獸醫專業人員的臨床參考。請務必對照最新藥品說明書及個別病患確認。
給藥途徑
Topical ophthalmic
禁忌症
- Hypersensitivity to carbomer or any component of the formulation (e.g., preservatives like cetrimide or benzalkonium chloride)
不良反應
- Transient blurred vision immediately after application
- Mild, temporary ocular irritation or stinging
- Crusting or matting of the eyelashes/eyelids
藥物相互作用
- Other topical ophthalmic medications · Carbomer gel can act as a physical barrier, reducing the absorption of other ophthalmic drops if applied simultaneously or prior to the drops. · moderate
監測
- Schirmer Tear Test (STT) to monitor tear production in KCS patients
- Resolution of clinical signs (conjunctival hyperemia, mucoid discharge, blepharospasm)
- Fluorescein staining to monitor for corneal ulceration
過量
Overdosage is not a clinical concern due to the lack of systemic absorption. Excess gel will simply spill over the eyelid margins and can be gently wiped away with a damp tissue.
VetSheet 藥物參考供持牌獸醫專業人員作臨床決策輔助之用,不能取代專業判斷或廠方最新藥品說明書。