甲殼素與碳酸鈣
這是一種結合甲殼素與碳酸鈣的口服粉劑，主要用於慢性腎病（CKD）犬貓的腸道磷結合劑與尿毒素吸附劑。通常在低磷飲食無法有效控制血磷時使用。
作用機制: Acts locally within the gastrointestinal tract. * **Calcium carbonate** binds to dietary phosphate in the gut → forms insoluble calcium phosphate → excreted in feces, thereby preventing systemic absorption of phosphorus. * **Chitosan** acts as an adsorbent for various uraemic toxins in the intestines, reducing their absorption and subsequent systemic accumulation.
各物種劑量
- Chronic kidney disease · 200 mg/kg · PO · q12h · Mixed with food
- Chronic kidney disease · 200 mg/kg · PO · q12h · Mixed with food
劑量為持牌獸醫專業人員的臨床參考。請務必對照最新藥品說明書及個別病患確認。
給藥途徑
禁忌症
- Pre-existing hypercalcaemia
不良反應
- Hypercalcaemia (due to calcium carbonate absorption)
藥物相互作用
- Calcitriol · Increased risk of hypercalcaemia when administered concurrently · major
監測
- Serum phosphate (at 4-6 week intervals to adjust dosage and achieve target concentrations)
- Serum total and ionized calcium (to monitor for hypercalcaemia)
過量
Overdosage primarily increases the risk of **hypercalcaemia** due to excessive calcium carbonate intake. Signs of hypercalcaemia may include polyuria, polydipsia, vomiting, lethargy, and weakness. Treatment involves discontinuing the supplement, feeding a low-calcium diet, and providing supportive fluid therapy (e.g., 0.9% NaCl) to promote calciuresis if clinically indicated.
VetSheet 藥物參考供持牌獸醫專業人員作臨床決策輔助之用,不能取代專業判斷或廠方最新藥品說明書。