色甘酸鈉
眼科抗過敏藥 / 肥大細胞穩定劑
色甘酸鈉是一種**肥大細胞穩定劑**,主要用於獸醫眼科以控制過敏性結膜炎。它不具備血管收縮、抗組織胺、環氧合酶 (COX) 抑制或其他直接的抗發炎特性。由於它是預防發炎介質的釋放,而非在受體層面阻斷其作用,因此在預防性或持續使用時效果最佳。
作用機制: Cromolyn sodium acts as a **mast cell stabilizer**. Upon antigen recognition, it blocks the degranulation of sensitized mast cells → prevents the release of **histamine** and **slow-reacting substance of anaphylaxis (SRS-A)** into the surrounding ocular tissues.
各物種劑量
Cats
- Relief of seasonal allergy / Allergic conjunctivitis · one drop 2-6 times daily · topical ophthalmic · q4-12h
Dogs
- Relief of seasonal allergy / Allergic conjunctivitis · one drop 2-6 times daily · topical ophthalmic · q4-12h
劑量為持牌獸醫專業人員的臨床參考。請務必對照最新藥品說明書及個別病患確認。
給藥途徑
topical ophthalmic
不良反應
- Stinging sensation upon application (low percentage of patients)
監測
- Resolution of clinical signs of allergic conjunctivitis (e.g., reduced hyperemia, chemosis, and pruritus)
過量
Overdose via the topical ophthalmic route is highly unlikely to cause systemic toxicity. Excess drops will simply wash out of the conjunctival sac.
VetSheet 藥物參考供持牌獸醫專業人員作臨床決策輔助之用,不能取代專業判斷或廠方最新藥品說明書。