益達胺
**益達胺**是一種廣泛使用的局部外用驅蟲藥，用於治療和預防犬貓的跳蚤感染。它可作為單一成分使用，或與莫昔克丁 (moxidectin)、百滅寧 (permethrin) 或氟氯苯菊酯 (flumethrin) 等其他抗寄生蟲藥物結合使用，以擴大其對抗壁蝨、蟎蟲和體內寄生蟲的抗菌譜。 > **警告：** 含有**百滅寧 (permethrin)** 的複方產品（例如 Advantix 蚤安）對貓具有高度毒性，**絕對不可**用於貓身上。 **臨床提示：** 為了達到最佳的跳蚤控制效果，強烈建議同時使用核准的昆蟲生長調節劑 (IGR) 並進行環境管理。所有接觸過的動物都應同時接受治療。
作用機制: Imidacloprid acts on the central nervous system of insects. It **binds to post-synaptic nicotinic acetylcholine receptors** → causes continuous nerve stimulation → results in **paralysis and death** of adult fleas and their larvae.
各物種劑量
- Treatment and prevention of flea infestations · Apply topically every 4 weeks · topical · q4 weeks · Ongoing · May be used in nursing bitches. Do not use in unweaned puppies <8 weeks.
- Treatment and prevention of flea infestations · Apply topically every 4 weeks · topical · q4 weeks · Ongoing · May be used in nursing queens. Do not use in unweaned kittens <8 weeks. NEVER use permethrin combinations.
劑量為持牌獸醫專業人員的臨床參考。請務必對照最新藥品說明書及個別病患確認。
給藥途徑
禁忌症
- Unweaned puppies and kittens <8 weeks of age (sole agent)
- Kittens <10 weeks or puppies <7 weeks of age (flumethrin collar)
- Pregnancy and lactation (flumethrin collar)
- Cats (permethrin combination products)
- Kittens <9 weeks or <1kg, puppies <7 weeks (moxidectin combination)
不良反應
- Transient pruritus at application site
- Erythema at application site
- Salivation (if ingested due to bitter taste)
- Transient lethargy
- Agitation
- Inappetence
監測
- Efficacy of flea control
- Application site for signs of irritation or erythema
過量
Overdose of the topical formulation is generally well tolerated, though application site reactions may be more pronounced. > **Toxicity Warning:** In the event of accidental ingestion of the combined product with flumethrin, **diazepam** should be administered to control neurological signs.
VetSheet 藥物參考供持牌獸醫專業人員作臨床決策輔助之用,不能取代專業判斷或廠方最新藥品說明書。