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聚乙烯醇

Polyvinyl alcohol

眼科潤滑劑 / 人工淚液Topical (Ophthalmic)

別名: Liquifilm Tears · Refresh Ophthalmic · Sno Tears · PVA

由 VetSheet 獸醫團隊審訂更新於 2026年4月5日本內容以實證獸醫文獻為本

1 drop per eyetopical· q1h· As needed

劑量為持牌獸醫專業人員的臨床參考。請務必對照最新藥品說明書及個別病患確認。

各物種劑量

🌎 NA — North America🌍 EU — Europe

適應症劑量途徑頻次療程地區
Keratoconjunctivitis sicca (KCS) / Dry eye lubrication1 drop per eyetopicalq1hAs needed🌍 EU
  • Keratoconjunctivitis sicca (KCS) / Dry eye lubrication: Patient compliance is poor if administered >q4h; consider using a longer acting tear replacement.

適應症劑量途徑頻次療程地區
Dry eye lubrication1 drop per eyetopicalq1hAs needed🌍 EU
  • Dry eye lubrication: Patient compliance is poor if administered >q4h; consider using a longer acting tear replacement.

劑量為持牌獸醫專業人員的臨床參考。請務必對照最新藥品說明書及個別病患確認。

正在為病患診症?VetSheet 的 AI 會把藥物、劑量與療程直接寫入結構化診症筆記。了解 VetSheet 如何運作

概覽

聚乙烯醇是一種合成的水性人工淚液,用於潤滑乾眼。在​乾眼症 (KCS)​ 的病例中,它能改善眼表潤滑、淚液滯留並提高病患舒適度,同時等待淚液刺激療法(如局部環孢素)發揮作用。

​臨床提示:​ 它比羥丙甲纖維素 (hypromellose) 更具附著力且黏度較低。然而,由於需要頻繁點眼(通常每小時一次),飼主依從性可能較差。如果無法頻繁給藥,請考慮使用長效型人工淚液(如交聯玻尿酸或卡波姆凝膠)。

作用機制

Acts as a lacromimetic (tear substitute). It mimics the aqueous layer of the trilaminar tear film, providing physical lubrication and moisture to the corneal and conjunctival surfaces.

安全性與警告

注意事項

Patient compliance is poor if administered >q4h; consider using a longer acting tear replacement.

Normal ophthalmic preparation handling precautions should be observed to prevent contamination of the dropper tip.

監測

  • Clinical signs of dry eye (corneal health, conjunctival hyperemia, comfort)
  • Schirmer tear test (STT) to monitor underlying KCS progression

藥物動力學

半衰期

Short (requires frequent reapplication)Short (requires frequent reapplication)

吸收

Acts locally on the ocular surface. Systemic absorption is negligible.

分佈

Remains on the corneal and conjunctival surfaces.

代謝

Not metabolized systemically.

排除

Cleared from the eye via the nasolacrimal duct and normal tear turnover.

過量

No specific information available. Overdose via topical ophthalmic administration is highly unlikely to cause systemic toxicity. Excess fluid will simply drain from the eye.

可用產品

劑型

  • Ophthalmic solution: 1.4% (0.4 ml vials, 15 ml bottle)

人用標示

  • Liquifilm Tears 1.4%
  • Refresh Ophthalmic 1.4%
  • Sno Tears 1.4%

各地核准狀態

United States✓ 已核准FDA

Available Over-The-Counter (OTC) as human artificial tears.

European Union✓ 已核准EMA

Human products used under the cascade.

United Kingdom✓ 已核准VMD

Classified as a Pharmacy (P) medicine in the UK for human use; used under the prescribing cascade in veterinary medicine.

暫無法規資料: 🇭🇰 HK · 🇹🇼 TW · 🇯🇵 JP · 🇰🇷 KR · 🇦🇺 AU

儲存與穩定性

Store at room temperature. Keep container tightly closed. Single-use vials should be discarded immediately after use if they do not contain preservatives.

飼主須知

聚乙烯醇是一種人工淚液,用於保持寵物眼睛濕潤,特別是針對患有「乾眼症」(KCS) 的寵物。

  • 在點眼藥水前後請​務必洗手​
  • ​請勿讓瓶口接觸​寵物的眼睛或任何表面,以免細菌污染。
  • 這些眼藥水通常需要非常頻繁地點(有時每小時一次)才能發揮效用。如果您覺得這個頻率難以配合,請與您的獸醫師討論是否有長效的替代方案。
  • 若需使用其他眼部藥物,請至少間隔 5-10 分鐘。

VetSheet 藥物參考供持牌獸醫專業人員作臨床決策輔助之用,不能取代專業判斷或廠方最新藥品說明書。