司可巴比妥與辛可卡因
這是一種由巴比妥類藥物（司可巴比妥）和局部麻醉劑（辛可卡因）組成的強效複方安樂死藥物，專門用於犬貓的人道安樂死。**臨床警告：** 此藥物對人類具有高度毒性，嚴禁意外自我注射。絕對不可用於一般麻醉。
作用機制: The combination works synergistically to ensure rapid and peaceful euthanasia: * **Secobarbital** → Rapidly and profoundly depresses the Central Nervous System (CNS), including the respiratory centers, leading to rapid loss of consciousness and cessation of respiration. * **Cinchocaine** → Exerts marked cardiotoxic effects at high doses. It depresses cardiac conduction → resulting in early cardiac arrest. **Clinical Pearl:** Because cardiac arrest is not dependent on the development of profound hypoxia, euthanasia with this combination is generally not accompanied by the agonal gasping that may occur with other agents.
各物種劑量
- Euthanasia · 0.25 ml/kg · IV · once · over 10-15 seconds · Administer over 10-15 seconds to minimize premature cardiac arrest. IV catheter recommended.
- Euthanasia · 0.25 ml/kg · IV · once · over 10-15 seconds · Administer over 10-15 seconds to minimize premature cardiac arrest. IV catheter recommended.
劑量為持牌獸醫專業人員的臨床參考。請務必對照最新藥品說明書及個別病患確認。
給藥途徑
禁忌症
- Must NOT be used for anesthesia (non-sterile and cardiotoxic)
不良反應
- Pain on injection (if administered perivascularly)
- Excitement (if administered perivascularly or too slowly)
監測
- Confirmation of cardiac arrest (auscultation)
- Confirmation of respiratory arrest
- Absence of corneal reflex
- Loss of pupillary light reflex
過量
Not applicable. This medication is intended to induce death.
VetSheet 藥物參考供持牌獸醫專業人員作臨床決策輔助之用,不能取代專業判斷或廠方最新藥品說明書。