次氯酸鈉 / 次氯酸
Sodium hypochlorite / Hypochlorous acid
Sodium hypochlorite
別名: Vetericyn · Renasan · Hypochlorous acid · HOCl
由 VetSheet 獸醫團隊審訂更新於 2026年4月5日本內容以實證獸醫文獻為本
劑量為持牌獸醫專業人員的臨床參考。請務必對照最新藥品說明書及個別病患確認。
各物種劑量
🌎 NA — North America🌍 EU — Europe
狗
| 適應症 | 劑量 | 途徑 | 頻次 | 療程 | 地區 |
|---|---|---|---|---|---|
| Wounds and skin infections | Spray affected areas | topical | bid | Until healed | 🌍 EU |
- Wounds and skin infections: Spray up to twice daily
貓
| 適應症 | 劑量 | 途徑 | 頻次 | 療程 | 地區 |
|---|---|---|---|---|---|
| Wounds and skin infections | Spray affected areas | topical | bid | Until healed | 🌍 EU |
- Wounds and skin infections: Spray up to twice daily
劑量為持牌獸醫專業人員的臨床參考。請務必對照最新藥品說明書及個別病患確認。
概覽
次氯酸鈉(以pH值平衡的次氯酸形式存在)是一種局部抗菌和傷口護理劑。它有助於透過清創機械性地清除皮膚和傷口表面的細胞碎片、衰老細胞、壞死組織和異物。它具有廣效的抗菌和抗黴菌作用。與傳統漂白水不同,現代獸醫用次氯酸配方經過pH值平衡,對癒合組織無細胞毒性。
作用機制
Hypochlorous acid (HOCl) is a potent oxidizing agent naturally produced by neutrophils during the oxidative burst.
- Mechanical action: The spray application assists in the physical debridement and flushing of cellular debris and necrotic tissue.
- Antimicrobial action: HOCl → oxidizes sulfhydryl enzymes and amino acids → disrupts bacterial cell walls and biofilms → leads to microbial cell death.
安全性與警告
禁忌症
- None reported
不良反應
- None reported
注意事項
Normal precautions should be observed.
Clinical Pearl: Do not mix with other topical medications, ointments, or cleansers (such as chlorhexidine or silver sulfadiazine) simultaneously, as the oxidative nature of hypochlorous acid may inactivate other active ingredients.
監測
- Wound healing progress
- Reduction in signs of local infection (erythema, purulent discharge)
- Signs of secondary or worsening infection requiring systemic therapy
藥物動力學
半衰期
吸收
Minimal to no systemic absorption when applied topically.
分佈
Remains localized to the site of application.
代謝
Rapidly neutralized by organic matter and cellular contact.
排除
Degrades into harmless salt and water.
過量
Overdosage is highly unlikely due to the topical route of administration and the non-toxic, physiological nature of the pH-balanced formulations. Ingestion of small amounts from grooming is generally considered safe.
可用產品
劑型
- Vetericyn VF spray (150 ppm free active chlorine)
- Vetericyn Regular spray (80 ppm free active chlorine)
- Renasan spray (140 ppm free active chlorine)
獸醫用
- Vetericyn VF (150 ppm free active chlorine) - 250 ml, 500 ml bottles
- Vetericyn Regular (80 ppm free active chlorine) - 89 ml, 236 ml, 473 ml bottles
- Renasan (140 ppm free active chlorine) - 60 ml, 100 ml, 250 ml, 500 ml, 750 ml bottles
各地核准狀態
Available Over-The-Counter (OTC)
Classified as GSL (General Sales List)
Classified as GSL (General Sales List)
暫無法規資料: 🇭🇰 HK · 🇹🇼 TW · 🇯🇵 JP · 🇰🇷 KR · 🇦🇺 AU
儲存與穩定性
Store at room temperature. Keep away from direct sunlight and extreme heat, as UV light and high temperatures can rapidly degrade the active free chlorine.
飼主須知
這是一種安全、無刺激性且無毒的噴霧,用於清潔寵物的傷口、割傷和皮膚感染。每天最多直接噴灑患處兩次,無需沖洗。如果寵物在噴灑後不慎舔舐該部位也是安全的。請將瓶子存放在避免陽光直射的地方。如果傷口惡化、發出異味或幾天後沒有癒合跡象,請聯繫您的獸醫。
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