依尼康唑
抗黴菌藥 (咪唑類)
**依尼康唑 (Enilconazole)** 是一種廣效的咪唑類抗黴菌藥物，主要在獸醫學中用於局部治療皮癬菌症（錢癬）。 **臨床要點：** 它對常見的獸醫皮癬菌（如犬小孢癬菌、石膏樣小孢癬菌和鬚毛癬菌）非常有效。通常以濃縮液形式提供，必須在稀釋後作為洗劑或浸泡劑使用。
作用機制: Inhibition of **cytochrome P450-dependent** synthesis of **ergosterol** in fungal cells → increased cell wall permeability → leakage of cellular contents → fungal cell death.
給藥途徑
Topical
禁忌症
- Known hypersensitivity to enilconazole or other imidazoles
不良反應
- Mild skin irritation (rare)
- Hypersalivation or vomiting if ingested
監測
- Resolution of skin lesions
- Negative fungal cultures (typically 2 consecutive negative cultures)
過量
Systemic toxicity is highly unlikely following topical application. Accidental ingestion of the concentrated solution may cause gastrointestinal irritation, vomiting, and hypersalivation. Treatment is symptomatic and supportive.
VetSheet 藥物參考供持牌獸醫專業人員作臨床決策輔助之用,不能取代專業判斷或廠方最新藥品說明書。