費洛蒙
Pheromones
Synthetic analogs of mammalian pheromones (fatty acids)
別名: Feliway · D.A.P. · Comfort Zone · Modipher EQ · Adaptil · FFP · Feline Facial Pheromone · Dog Appeasing Pheromone · EAP · Equine Appeasing Pheromone · Canine appeasing pheromone
由 VetSheet 獸醫團隊審訂更新於 2026年4月5日本內容以實證獸醫文獻為本
劑量為合格獸醫專業人員的臨床參考。請務必對照最新仿單及個別病患確認。
各物種劑量
🌎 NA — North America🌍 EU — Europe
狗
| 適應症 | 劑量 | 途徑 | 頻次 | 療程 | 地區 |
|---|---|---|---|---|---|
| Fear, stress, separation anxiety, new environments | 1 diffuser per 500-650 sq. ft. | Environmental | Continuous | Vial lasts approx 4 weeks | 🌎 NA |
| Travel anxiety, unfamiliar places | Spray in car, kennels, crates, or on bandanas | Environmental | 20 minutes prior to travel, or twice daily in new areas | As needed | 🌎 NA |
| Stress associated with separation, noise sensitivity, travel, new home, or veterinary visits | Apply via diffuser, spray, or collar as directed | topical | Continuous (diffuser/collar) or as needed (spray) | 3 months recommended for attachment-related issues | 🌍 EU |
- Fear, stress, separation anxiety, new environments: Plug into electric outlet in the room most often used by the animal. May require up to 72 hours to saturate area.
- Travel anxiety, unfamiliar places: Do not spray directly on dogs.
- Stress associated with separation, noise sensitivity, travel, new home, or veterinary visits: Diffuser: place in most occupied room. Spray: use on bedding, cages, cars (do not spray on dog). Collar: useful for reactions outside the home; if multiple dogs are affected, each should wear a collar.
貓
| 適應症 | 劑量 | 途徑 | 頻次 | 療程 | 地區 |
|---|---|---|---|---|---|
| Urine marking, scratching, stress, inter-cat aggression | 1 diffuser per 500-650 sq. ft. | Environmental | Continuous | Vial lasts approx 4 weeks | 🌎 NA |
| Urine marking, prominent objects | 1 spray per application site | Environmental | 1-2 times daily | 30 days | 🌎 NA |
- Urine marking, scratching, stress, inter-cat aggression: Plug into electric outlet in the room most often used by the animal. May require up to 72 hours to saturate area.
- Urine marking, prominent objects: Pump spray approx 4 inches from site, 8 inches from floor. Do not spray directly on cats. Maintenance sprays every 2-3 days may be required.
馬
| 適應症 | 劑量 | 途徑 | 頻次 | 療程 | 地區 |
|---|---|---|---|---|---|
| Stressful situations (transport, shoeing, clipping, training) | 2 sprays into each nostril | Intranasal | 1/2 hour before anticipated stress or event | As needed | 🌎 NA |
- Stressful situations (transport, shoeing, clipping, training): Keep horse in a non-stressful environment for 1/2 hour after administration to achieve best results.
劑量為合格獸醫專業人員的臨床參考。請務必對照最新仿單及個別病患確認。
概覽
市售的費洛蒙是天然哺乳動物安撫和面部費洛蒙的合成類似物。它們作為非全身性、高度安全的輔助工具，用於減輕獸醫病患的焦慮、壓力和不良行為。
- 貓：可用於尿液標記、垂直抓撓、貓際攻擊和一般壓力。
- 狗：用於分離焦慮、噪音恐懼、旅行壓力以及在新環境中的安撫。
- 馬：有助於緩解運輸、釘蹄、修剪和訓練期間的壓力。
臨床提示：費洛蒙並非解決嚴重行為問題的萬靈丹。當它們作為綜合行為矯正計畫的一部分（可能與全身性抗焦慮藥物併用）時，效果最佳。
作用機轉
Pheromones are detected by the vomeronasal organ (VNO) or Jacobson's organ, located in the hard palate/nasal cavity.
Detection by the VNO → transmission via accessory olfactory bulb → amygdala and hypothalamus → modulation of emotional response (general calming effect).
- F3 Feline Facial Pheromone: Inhibits urine marking, encourages feeding, and enhances exploratory behavior.
- F4 Feline Pheromone: An allomarking pheromone that familiarizes cats with their surroundings and conspecifics.
- Dog Appeasing Pheromone (DAP): Analog of bitch intermammary pheromone produced during nursing, providing a sense of safety and comfort.
安全性與警告
禁忌症
- None known
不良反應
- No significant adverse effects reported
- Highly safe due to lack of systemic absorption
注意事項
Do not spray directly on cats or dogs. When using sprays, allow the alcohol carrier to evaporate (approx. 15-20 minutes) before introducing the animal to the area. Diffusers may require up to 72 hours to fully saturate a room, so effects may not be immediate. Do not plug diffusers behind furniture or under curtains.
藥物交互作用
May reduce or negate the calming effects of pheromones
Anecdotal reports suggest a synergistic anxiolytic action
監測
- Clinical efficacy (reduction in targeted stress or anxiety behaviors)
藥物動力學
吸收
Not systemically absorbed; acts locally on the vomeronasal organ.
過量
No specific animal toxicity data is available. The ingredients are not considered toxic. If humans are accidentally exposed and experience an adverse reaction, they should contact a physician or poison control center.
可用產品
劑型
- Electric Diffuser
- Environmental Spray
- Collar
- Intranasal Spray (Equine)
獸醫用
- Feliway Diffuser (48 mL vial)
- Comfort Zone Feline
- Feliway Spray 10% (75 mL)
- Comfort Zone Spray for Cats
- D.A.P. Diffuser (48 mL vial)
- D.A.P. Spray 2% (60 mL)
- Comfort Zone Spray for Dogs
- Comfort Zone Canine
- D.A.P. Collar
- Modipher EQ Mist with E.A.P. 0.1% (7.5 mL)
各地核准狀態
General sale
General sale
暫無法規資料: 🇺🇸 US · 🇭🇰 HK · 🇹🇼 TW · 🇯🇵 JP · 🇰🇷 KR · 🇦🇺 AU
儲存與穩定性
Store at room temperature. Do not mix with other ingredients or substances. Keep out of reach of children.
飼主須知
費洛蒙是天然的「安撫信號」，能幫助寵物感到安全和安心。
- 擴香插劑：將擴香插劑插在寵物最常待的房間內無遮蔽的插座上。請勿將其放置在家具後方或窗簾下方，因為蒸氣需要空間上升。房間可能需要長達3天的時間才能完全充滿費洛蒙，請耐心等待。
- 噴霧劑：絕對不要直接噴在貓或狗身上。 如果用於旅行，請在將寵物放入提籠或車內前15-20分鐘噴灑。這能讓氣味強烈的酒精載體揮發，只留下無味的費洛蒙。
- 預期效果：費洛蒙是一個極佳的輔助工具，但與正向增強訓練和環境管理結合使用時效果最好。
VetSheet 藥物參考供合格獸醫專業人員作臨床決策輔助之用，不能取代專業判斷或廠商最新仿單。