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磷酸鈉灌腸液

Sodium Phosphate Enema

Sodium acid phosphate / Sodium phosphate

滲透性瀉藥Rectal狗貓

別名: Fleet Enema · Fletchers' Phosphate Enema · Sodium biphosphate · Sodium dihydrogen phosphate

由 VetSheet 獸醫團隊審訂更新於 2026年4月5日本內容以實證獸醫文獻為本

60-128 mlRectal· Single dose· As needed
60–128 ml — 每隻動物的固定劑量（不按體重換算）

劑量為合格獸醫專業人員的臨床參考。請務必對照最新仿單及個別病患確認。

各物種劑量

🌎 NA — North America🌍 EU — Europe

狗

適應症劑量途徑頻次療程地區
Cathartic / rapid emptying of the colon60-128 mlRectalSingle doseAs needed🌍 EU
Cathartic / rapid emptying of the colon128 mlRectalSingle doseAs needed🌍 EU
  • Cathartic / rapid emptying of the colon: For dogs 5-10 kg. Do not use in dogs < 5 kg.
  • Cathartic / rapid emptying of the colon: For dogs > 10 kg.

貓

適應症劑量途徑頻次療程地區
ContraindicatedDO NOT USERectalN/AN/A🌍 EU
  • Contraindicated: Fatal electrolyte abnormalities (hypocalcaemia and hyperphosphataemia) can occur.

劑量為合格獸醫專業人員的臨床參考。請務必對照最新仿單及個別病患確認。

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概覽

磷酸鈉灌腸液是一種​滲透性瀉藥​，用於引發犬隻結腸的快速排空。

​臨床警告：​ 嚴禁使用於貓及小型犬（< 5公斤），因為有引發致命性電解質異常（嚴重高血磷和低血鈣）的極高風險。

作用機轉

Acts as a hyperosmotic agent in the rectum and colon.

  • Draws water into the colonic lumen via osmosis → increases intraluminal volume and pressure → stimulates mechanoreceptors → induces peristalsis and rapid bowel evacuation.

安全性與警告

禁忌症

  • Cats (strictly contraindicated)
  • Small dogs (< 5 kg)
  • Dehydrated patients
  • Patients with severe renal impairment
  • Patients with compromised colonic mucosal integrity

不良反應

  • Hyperphosphatemia
  • Hypocalcemia
  • Hypernatremia
  • Dehydration
  • Fatal electrolyte imbalances in sensitive species

注意事項

​WARNING:​ Absorption of phosphate and sodium can occur across the colonic mucosa. This can lead to life-threatening hyperphosphatemia, hypocalcemia, and hypernatremia, particularly in cats, small dogs, or patients with compromised renal function or severe dehydration.

​Clinical Pearl:​ Always ensure the patient is adequately hydrated before and after administration.

監測

  • Serum calcium
  • Serum phosphorus
  • Serum sodium
  • Hydration status
  • ECG (if hypocalcemia is suspected)

藥物動力學

半衰期

貓Not established狗Not established

吸收

Intended for local action in the colon, but significant systemic absorption of sodium and phosphate can occur across the colonic mucosa, especially if retained for prolonged periods or if mucosal integrity is compromised.

分佈

Absorbed electrolytes distribute into the extracellular fluid.

代謝

Not metabolized.

排除

Absorbed phosphate and sodium are primarily excreted by the kidneys. Unabsorbed portion is excreted in feces.

過量

Overdosage or administration to contraindicated species (cats, small dogs) leads to severe hyperphosphatemia, hypocalcemia, and hypernatremia. Clinical signs include weakness, tremors, tetany, seizures, cardiac arrhythmias, shock, and death.

​Treatment:​ Aggressive IV fluid therapy (e.g., 0.9% NaCl) to correct dehydration and hypernatremia, and IV calcium gluconate to treat life-threatening hypocalcemia. Monitor electrolytes closely.

可用產品

劑型

  • Rectal tube: 133 ml containing 21.4 g sodium acid phosphate and 9.4 g sodium phosphate
  • Rectal tube: 128 ml containing 12.8 g sodium acid phosphate and 10.24 g sodium phosphate

人用標示

  • Fleet Enema (133 ml)
  • Fletchers' Phosphate Enema (128 ml)

各地核准狀態

European Union✓ 已核准處方藥EMA

Human authorized products used off-label under the cascade.

United Kingdom✓ 已核准處方藥VMD

Human authorized products (P category) used off-label under the cascade.

暫無法規資料: 🇺🇸 US · 🇭🇰 HK · 🇹🇼 TW · 🇯🇵 JP · 🇰🇷 KR · 🇦🇺 AU

儲存與穩定性

Store at room temperature. Do not freeze.

飼主須知

此藥物用於緩解嚴重便秘或在手術前清理腸道。

​危險警告：​ 除非獸醫明確指示，否則切勿將人類灌腸產品（如 Fleet）用於貓或小型犬。這可能導致血液中鹽分發生快速且致命的變化。

  • 僅給予處方的準確劑量。
  • 確保您的狗有充足的新鮮飲水以防脫水。

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